PAIN PERCEPTION THRESHOLD IN MAJOR DEPRESSION
PAIN PERCEPTION THRESHOLD IN MAJOR DEPRESSION
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DOI：
10.1016/0006-3223(93)90041-b
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发表时间：
1993-11-15
影响因子：
10.6
通讯作者：
GATTAZ, WF
中科院分区：
文献类型：
--
作者：
ADLER, G;GATTAZ, WF
对16例抑郁症患者的躯体感觉阈值(SPT)和痛觉阈值(PPT)进行了研究，并与年龄匹配、性别匹配的对照组进行了比较，并与汉密尔顿抑郁量表评定的精神病理状态进行了比较。知觉阈值通过无创高频皮肤电刺激进行评估。患者的绝对知觉阈值提高。而相对痛觉阈值(RPPT=PPT：SPT)显著降低。RPPT与发育迟缓呈正相关。它与焦虑呈负相关，这表明抑郁症患者疼痛感知阈值的降低可能归因于焦虑和压力应对能力受损。
Somatosensory perception threshold (SPT) and pain perception threshold (PPT) were studied in 16 patients with major depression, compared to the findings in an age-matched and gender-matched control group and related to the psychopathological state evaluated by means of the Hamilton Depression Scale. Perception thresholds were assessed by means of a noninvasive high-frequency electric skin stimulation. Absolute perception thresholds were increased in the patients. However, the relative pain perception threshold (RPPT = PPT : SPT) was significantly reduced. RPPT was positively correlated with retardation. It was negatively correlated with anxiety, suggesting that a reduction of pain perception thresholds in depressive patients may be attributed to anxiety and impaired stress-coping.