Daily weight gain and protein catabolic rate are lower over the long interdialytic interval.
Daily weight gain and protein catabolic rate are lower over the long interdialytic interval.
复制标题
在较长的透析间隔期间，每日体重增加和蛋白质分解代谢率较低。
DOI：
10.5414/cnp60022
复制
发表时间：
2003
影响因子：
1.1
通讯作者：
M. Jadoul
中科院分区：
文献类型：
--
作者：
A. Stragier;M. Jadoul
BACKGROUND
The interdialytic weight gain (IDWG) and protein catabolic rate (PCR), expressed per 24 hours (daily), are usually assumed to be stable over the week in chronic hemodialysis (HD) patients.
METHODS
We studied different HD patient groups at different time points (study 1 in 1993: n = 48, study 2 in 1999: n = 16, study 3 in 2000: n = 112). Daily IDWG (calculated from post- and pre-dialysis body weight and interdialytic interval) and nPCR (calculated from kinetic modeling) were compared over short (2 days) and long (3 days) intervals.
RESULTS
In all groups of HD patients studied, both daily IDWG and nPCR were significantly (p < 0.05) lower (IDWG by 7-15%, nPCR by 5-6%) over long than short interdialytic intervals. This difference was observed whether or not blood sampling was planned after the long interval. This suggests selfrestriction of dietary intake over the long interdialytic interval.
CONCLUSIONS
Daily IDWG and nPCR are lower over the long interdialytic interval. Studies should thus define or even standardize the period of time over which IDWG and nPCR are calculated.
