Tunable fluorescence upon aggregation: Photophysical properties of cationic conjugated polyelectrolytes containing AIE and ACQ units and their use in the dual-channel quantification of heparin
Tunable fluorescence upon aggregation: Photophysical properties of cationic conjugated polyelectrolytes containing AIE and ACQ units and their use in the dual-channel quantification of heparin
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DOI：
10.1016/j.snb.2014.03.004
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发表时间：
2014-07-01
影响因子：
8.4
通讯作者：
Dong, Yuping
中科院分区：
文献类型：
--
作者：
Shi, Jianbing;Wu, Yanmei;Dong, Yuping
通过对中性聚合物进行季铵化，合成了一系列以四苯乙烯（TPE）为聚集诱导发光（AIE）单元，芴（F）为聚集猝灭（ACQ）单元的阳离子共轭聚电解质PTPExFyN。这些阳离子共轭聚电解质表现出聚集诱导发射增强（AIEE）和双通道荧光响应（DCFR）时，在溶液中聚集，无论是通过添加非溶剂或通过添加肝素。荧光滴定曲线中PTPEN或PTPE0.5F0.5N的荧光强度与肝素浓度呈线性递增关系，而PTPE0.3F0.7N、PTPE0.2F0.8N和PTPE0.1F0.9N的荧光强度呈DCFR（即，两个独立的线性关系），一个归因于ACQ信号，另一个归因于AIEE信号。利用PTPExFyN在溶液和聚集态的光致发光（PL）量子产率和寿命的实验数据，通过计算辐射和非辐射衰减速率常数，研究了AIEE的机理.最后，证明了成功的定量肝素的PTPE0.2F0.8N溶液，表现出良好的线性和灵敏度。(C)2014爱思唯尔有限公司版权所有。
A series of cationic conjugated polyelectrolytes named as PTPExFyN, which consist of tetraphenylethylene (TPE) as aggregation-induced emission (AIE) units and fluorene (F) as aggregation-caused quenching (ACQ) units, have been synthesized by the quaternization of the corresponding neutral polymers. These cationic conjugated polyelectrolytes exhibited aggregation-induced emission enhancement (AIEE) and dual-channel fluorescence response (DCFR) when aggregated in solution, either by adding non-solvent or by adding heparin. The fluorescence intensity of PTPEN or PTPE0.5F0.5N in the fluorescence titration curves showed a linear increasing relationship with the concentration of heparin, while the fluorescence intensity of PTPE0.3F0.7N, PTPE0.2F0.8N and PTPE0.1F0.9N showed DCFR (i.e., two independent linear relationships) with the concentration of heparin, one attributed to the ACQ signal and the other attributed to the AIEE signal. The mechanism of AIEE was investigated by calculating the radiative and nonradiative decay rate constants using the experimental data of photoluminescence (PL) quantum yields and lifetimes of PTPExFyN in solution and aggregation state. At last, the successful quantification of heparin by the PTPE0.2F0.8N solution was demonstrated, which showed good linearity and sensitivity. (C) 2014 Elsevier B.V. All rights reserved.