Estimation of various mechanical characteristics of human bones using dual energy X-ray absorptiometry: Methodology and precision

Estimation of various mechanical characteristics of human bones using dual energy X-ray absorptiometry: Methodology and precision
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DOI:
10.1016/8756-3282(95)00376-2
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发表时间:
1996-01-01
期刊:
影响因子:
4.1
通讯作者:
Vuori, I
Vuori, I
中科院分区:
医学2区
文献类型:
--
作者:
Sievanen, H;Kannus, P;Vuori, I

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骨的力学能力是由给定骨骼部位的宏观几何特征[大小、形状、表观密度(BMAD)、皮质厚度(CWT)、横截面积、骨小梁结构]、固有材料特性(刚度、强度)和载荷条件(模式、方向、速率)决定的。本研究的主要目的是介绍进一步分析双能X射线吸收(DXA)数据的精确方法,以及评估代表轴向和附件骨骼的几个骨骼部位的骨的宏观力学特性。本研究表明,使用计算的BMAD、CWT和尺寸参数,典型长骨的不同部位特定的力学特性(刚度和强度指数)可以用较低的精度误差来近似(通常
The mechanical competence of bone is determined by its macroscopic geometric characteristics [size, shape, apparent density (BMAD), cortical thickness (CWT), cross-sectional area, trabecular architecture], intrinsic material properties (stiffness, strength), and loading conditions (mode, direction, rate) at a given skeletal site, The main objective of this study was to introduce precise methods for further analysis of dual energy X-ray absorptiometric (DXA) data and for estimating macroscopic mechanical characteristics of bone at several skeletal sites representing both the axial and appendicular skeleton, This study showed that using computational BMAD, CWT and dimensional parameters, different site-specific mechanical charateristics (stiffness and strength indices) of a typical long bone (a bone consisting of both the cortical shaft and trabecular metaphyses and epiphyses at both ends) can be approximated with a low precision error (generally