Effects of hemodialysis therapy on sit-to-walk characteristics in end stage renal disease patients.
Effects of hemodialysis therapy on sit-to-walk characteristics in end stage renal disease patients.
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DOI：
10.1007/s10439-012-0701-6
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发表时间：
2013-04
影响因子：
3.8
通讯作者：
Abdel-Rahman, Emaad M.
中科院分区：
文献类型：
--
作者：
Soangra, Rahul;Lockhart, Thurmon E.;Lach, John;Abdel-Rahman, Emaad M.
接受血液透析（HD）的终末期肾病（ESRD）患者由于多种原因而具有较高的发病率和死亡率;其中之一是跌倒率明显高于一般人群。尽管为降低ESRD患者的高死亡率和改善其生活质量做出了许多努力，但取得的成功有限。如果要达到预防跌倒的充分干预，必须了解这一人群中与福尔斯一致的功能和活动机制。人体运动，如从坐到走（STW）任务具有临床意义，对这些运动的分析为具有提示跌倒风险的功能限制的老年患者的姿势和运动性能提供了有意义的评价。为了评估HD治疗对跌倒风险的影响，使用定制的惯性测量单元（IMU）在6名ESRD患者中获得了22次HD前后测量。采用系综经验模式分解和Savistky-Golay滤波方法对IMU信号进行去噪，以检测相关事件，从而识别STW相。结果表明，透析治疗后，患者离开椅子的速度较慢（通过躯干屈曲角加速度、达到躯干屈曲峰值的时间和总体STW完成时间测量）。STW是日常生活活动中的常见运动，HD治疗可能会影响这些运动的姿势和运动控制。STW运动的分析不仅可以帮助评估患者的身体状况，还可以帮助识别HD相关的跌倒风险。这项初步研究提出了一种非侵入性的运动学测量方法，用于早期检测ESRD患者的跌倒风险增加，使用便携式惯性传感器进行门诊监测。这可能有助于更好地了解发病机制，并提高卫生保健提供者在确定跌倒风险个体的针对性干预措施方面的意识。
Patients with end stage renal diseases (ESRD) undergoing hemodialysis (HD) have high morbidity and mortality due to multiple causes; one of which is dramatically higher fall rates than the general population. In spite of the multiple efforts aiming to decrease the high mortality and improve quality of life in ESRD patients, limited success has been achieved. If adequate interventions for fall prevention are to be achieved, the functional and mobility mechanisms consistent with falls in this population must be understood. Human movements such as sit-to-walk (STW) tasks are clinically significant, and analysis of these movements provides a meaningful evaluation of postural and locomotor performance in elderly patients with functional limitations indicative of fall risks. In order to assess the effects of HD therapy on fall risks, 22 sessions of both pre- and post-HD measurements were obtained in six ESRD patients utilizing customized inertial measurement units (IMU). IMU signals were denoised using ensemble empirical mode decomposition and Savistky-Golay filtering methods to detect relevant events for identification of STW phases. The results indicated that patients were slower to get out of the chair (as measured by trunk flexion angular accelerations, time to peak trunk flexion, and overall STW completion time) following the dialysis therapy session. STW is a frequent movement in activities of daily living, and HD therapy may influence the postural and locomotor control of these movements. The analysis of STW movement may assist in not only assessing a patient’s physical status, but in identifying HD-related fall risk as well. This preliminary study presents a non-invasive method of kinematic measurement for early detection of increased fall risk in ESRD patients using portable inertial sensors for out-patient monitoring. This can be helpful in understanding the pathogenesis better, and improve awareness in health care providers in targeting interventions to identify individuals at risk for fall.
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影响因子：
19.6
作者：
Johansen, KL;Shubert, T;Kent-Braun, JA
通讯作者：
Kent-Braun, JA
影响因子：
1.8
作者：
Fordyce, AM;Lalani, Z;Hawkesford, JE
通讯作者：
Hawkesford, JE
影响因子：
1.8
作者：
Hass, Chris J.;Waddell, Dwight E.;Gregor, Robert J.
通讯作者：
Gregor, Robert J.
影响因子：
2.4
作者：
Buckley, Thomas;Pitsikoulis, Chris;Hass, Chris J.
通讯作者：
Hass, Chris J.
影响因子：
13.2
作者：
Desmet, C;Beguin, C;Jadoul, M
通讯作者：
Jadoul, M