Changes in cognitive function during the 1-year period following endarterectomy and stenting of patients with high-grade carotid artery stenosis
Changes in cognitive function during the 1-year period following endarterectomy and stenting of patients with high-grade carotid artery stenosis
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DOI：
10.1007/s00701-009-0420-4
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发表时间：
2009-12-01
影响因子：
2.4
通讯作者：
Endo, Shunro
中科院分区：
文献类型：
--
作者：
Takaiwa, Akiko;Hayashi, Nakamasa;Endo, Shunro
在重度颈动脉狭窄患者中，注意到治疗前后认知功能下降和认知功能变化，但此类患者治疗的真实效果尚不清楚。对26例颈动脉狭窄患者行颈动脉内膜剥脱术（CEA）和支架置入术（CAS），于治疗前、治疗后1周、3个月、6个月和1年进行认知功能检查。结果表明：（1）治疗前患者的RBANS评分平均偏低，认知功能损害较轻，但较弥散;（2）CEA和CAS术后3个月RBANS评分显著提高，认知功能改善持续1年以上;颈动脉重度狭窄患者认知功能轻度下降，经CEA和CAS治疗后，其症状明显改善。RBANS是适合此类患者的测试组合。
In patients with severe carotid artery stenosis, cognitive decline and changes in cognitive function before to after treatment have been noted, though the true effects of treatment in such patients remain unclear. A convenient and repeatable neuropsychological test battery is needed for such patients.In 26 patients with severe carotid artery stenosis treated by carotid endarterectomy (CEA) and stenting (CAS), cognitive function was examined before and 1 week, 3 months, 6 months, and 1 year after treatment. RBANS and MMSE were selected as a test battery, and changes in test scores and long-term results of revascularization were evaluated.RBANS was useful and suitable for neuropsychological testing in such patients, and yielded the following results: (1) Patients before treatment had, on average, RBANS scores rated low average, with mild but relatively diffuse cognitive impairment; (2) RBANS scores were increased significantly at 3 months after CEA and CAS, and cognitive improvement was maintained over 1 year; and (3) scores were decreased temporarily at 1 week after CEA, but not after CAS.Patients with severe carotid artery stenosis exhibited mild decline in cognitive function, which was improved after CEA and CAS. RBANS is a suitable test battery for this type of patient.