An epidemiologic investigation of alcohol‐dependent schizophrenics

An epidemiologic investigation of alcohol‐dependent schizophrenics
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酒精依赖型精神分裂症患者的流行病学调查

DOI:
--
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发表时间:
1989
影响因子:
6.7
通讯作者:
J. A. McGrath
J. A. McGrath
中科院分区:
医学1区
文献类型:
--
作者:
A. Pulver;P. Wolyniec;M. G. Wagner;C. Moorman;J. A. McGrath

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摘要——大多数临床医生都认为精神分裂症患者经常酗酒。然而,人们对这一群体的临床或家族特征知之甚少。我们比较了酒精性精神分裂症和非酒精性精神分裂症的社会人口学和临床特征以及其一级亲属中各种精神疾病的发生率。社会人口统计学特征的唯一差异是酒精性精神分裂症患者中男性比例较高。临床上,酒精性精神分裂症患者更有可能出现幻觉、抑郁发作、躁狂发作(仅限女性)和多种药物滥用(仅限男性)。此外,男性酒精性精神分裂症患者首次住院时间比男性非酒精性精神分裂症患者更年轻。这种效应对于女性来说则相反。酒精性精神分裂症患者的亲属酗酒的可能性是非酒精性精神分裂症患者亲属的 2.6 倍。两组其他精神疾病的发病率相似。
ABSTRACT– Most clinicians agree that alcoholism is frequent in schizophrenic patients. However, little is known about the clinical or familial characteristics of this group. We compared alcoholic schizophrenics and nonalcoholic schizophrenics with respect to sociodemographic and clinical characteristics and the rate of various psychiatric illnesses among their first‐degree relatives. The only difference in the sociodemographic characteristics was a higher proportion of males among the alcoholic schizophrenics. Clinically, the alcoholic schizophrenics were more likely to report experiencing hallucinations, depressive episodes, manic episodes (females only) and multiple substance abuse (males only). In addition, the male alcoholic schizophrenics were younger at first hospitalization than the male nonalcoholic schizophrenics. This effect was reversed for females. The relatives of alcoholic schizophrenics were 2.6 times more likely to be alcoholic than the relatives of the nonalcoholic schizophrenics. The morbidity for other psychiatric disorders was similar in the two groups.
DOI: --
发表时间: 1972
期刊: --
影响因子: --
作者:
D. Cox
通讯作者: D. Cox
DOI: 10.1001/archpsyc.1988.01800280095013
发表时间: 1988
影响因子: --
作者:
Kendler,KS
通讯作者: Kendler,KS
继发性抑郁症的酗酒患者。
DOI: 10.1176/ajp.140.6.711
发表时间: 1983
期刊: The American journal of psychiatry
影响因子: --
作者:
Schuckit,M
通讯作者: Schuckit,M