Visualization and detectability of elements rarely contained in soft tissue by X-ray scanning analytical microscopy and electron-probe micro analysis.
Visualization and detectability of elements rarely contained in soft tissue by X-ray scanning analytical microscopy and electron-probe micro analysis.
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通过 X 射线扫描分析显微镜和电子探针微分析对软组织中很少含有的元素进行可视化和可检测性。
DOI：
10.1016/s0142-9612(00)00349-5
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发表时间：
2001
期刊：
影响因子：
14
通讯作者：
T. Kawasaki
中科院分区：
文献类型：
--
作者：
M. Uo;F. Watari;A. Yokoyama;H. Matsuno;T. Kawasaki
比较了X射线扫描分析显微镜（XSAM）和电子探针（EPMA）对软组织中微量元素的检测能力。XSAM和EPMA可获得大鼠正常软组织中Ca、S、P和镍植入软组织中溶解镍的标测图像。EPMA对P的检测灵敏度较高，而XSAM对Ca、S和Ni的定位灵敏度较高，为上级。XSAM对重元素的高探测能力是由XSAM产生的大量特征X射线和来自重元素的特征X射线的低衰减来解释的。XSAM可以为低浓度的重元素提供更清晰的映射图像，而不会对样品造成辐射损伤。
The detectability of elements rarely contained in soft tissue was compared using X-ray scanning analytical microscope (XSAM) and electron-probe micro analysis (EPMA). Mapping images of Ca, S and P in normal soft tissue of the rat and dissolved Ni in Ni implanted soft tissue could be obtained by XSAM and EPMA. EPMA was more sensitive in detection of P, while XSAM was superior for Ca, S and Ni mapping. The high detectability for heavier elements by XSAM was explained by the large volume of characteristic X-ray generation in XSAM and low attenuation of the characteristic X-rays from heavier elements. XSAM could provide clearer mapping images for heavier elements whose concentration was low without radiation damage to specimens.