Infectious agents associated with myopathies
Infectious agents associated with myopathies
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DOI：
10.1097/00002281-199611000-00003
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发表时间：
1996-01-01
影响因子：
5.1
通讯作者：
Ytterberg, Steven R.
中科院分区：
文献类型：
--
作者：
Ytterberg, Steven R.
几种传染性病原体可引起慢性或急性肌病。目前对特发性炎性肌病可能的感染原因的研究主要集中在逆转录病毒，包括HIV和人类T细胞白血病-淋巴瘤病毒I型。在这两种情况下，病毒可能不会直接感染肌肉纤维，而是诱导免疫介导的肌炎。其他的兴趣集中在肠道病毒作为特发性炎性肌病的潜在病原体，但它们与人类肌炎的关系尚不清楚。除慢性肌肉疾病外，几种传染性病原体可引起急性肌炎，包括化脓性肌炎（在温带气候中越来越常见）和横纹肌溶解症。
Several infectious agents can cause chronic or acute myopathy. Most current investigations into possible infectious causes of the idiopathic inflammatory myopathies have focused on retroviruses, including HIV and human T-cell leukemia-lymphoma virus type I. In both cases, viruses likely do not directly infect muscle fibers but instead induce an immunologically mediated myositis. Other interest has focused on enteroviruses as potential etiologic agents of idiopathic inflammatory myopathy, but their relationship to human myositis is less clear. In addition to chronic muscle disease, several infectious agents can cause acute myositis, including pyomyositis, which is being recognized in temperate climates with increasing frequency, and rhabdomyolysis.