Alignment and small oscillation of superparamagnetic iron oxide nanoparticle in liquid under alternating magnetic field
Alignment and small oscillation of superparamagnetic iron oxide nanoparticle in liquid under alternating magnetic field
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DOI：
10.1063/1.5079899
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发表时间：
2019-03
影响因子：
3.2
通讯作者：
M. Suwa;A. Uotani;S. Tsukahara
中科院分区：
文献类型：
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作者：
M. Suwa;A. Uotani;S. Tsukahara
磁性纳米粒子在交变磁场中的旋转行为对于其在生物医学领域的成功应用具有重要意义。这些应用包括磁热疗和磁粒子成像。特别是，最近的理论研究表明，MNP本身的物理旋转导致MNP的磁化响应的显着变化。然而，由于很难区分物理旋转对磁化曲线的贡献，因此迄今为止尚未建立其在交变场下的行为。在这项研究中，我们测量了磁赤铁矿MNP悬浮液的吸光度变化。我们在法拉第结构的阻尼振荡磁场（DOMF）中观察到了磁致线性二向色性，其中光的传播平行于磁场。随着DOMF的应用，观察到吸光度的变化。通过数值模拟，发现吸光度变化的波形反映了物理旋转的行为。从波形分析中，实验发现，MNP的易磁化轴在交变磁场下部分排列并以小幅度振荡。根据所观察到的吸光度变化波形，提出了交变磁场下MNP在液体中的旋转机理。研究了磁性纳米粒子在交变磁场中的旋转行为，并探讨了粘度和磁场频率对磁性纳米粒子旋转行为的影响，证实了上述结果与磁性纳米粒子在交变磁场中的旋转机理是一致的，这对于磁性纳米粒子在生物医学领域的成功应用具有重要意义。这些应用包括磁热疗和磁粒子成像。特别是，最近的理论研究表明，MNP本身的物理旋转导致MNP的磁化响应的显着变化。然而，由于很难区分物理旋转对磁化曲线的贡献，因此迄今为止尚未建立其在交变场下的行为。在这项研究中，我们测量了磁赤铁矿MNP悬浮液的吸光度变化。我们在法拉第结构的阻尼振荡磁场（DOMF）中观察到了磁致线性二向色性，其中光的传播平行于磁场。随着DOMF的应用，观察到吸光度的变化。通过数值模拟，结果显示...
It is important to understand the rotational behavior of magnetic nanoparticles (MNPs) in liquids under an alternating magnetic field for their successful application in biomedical fields. These applications include magnetic hyperthermia therapy and magnetic particle imaging. In particular, recent theoretical studies suggest that the physical rotation of MNP itself causes a significant change in the magnetization response of MNPs. However, because it is hard to distinguish the contribution of the physical rotation to the magnetization curve, its behavior under an alternating field has not been established to date. In this study, we measured the absorbance change of maghemite MNP suspension. We observed magnetically induced linear dichroism under a damped oscillatory magnetic field (DOMF) with Faraday configuration, where the propagation of light was parallel to the magnetic field. Accompanied by the application of DOMF, an absorbance change was observed. Through numerical simulations, it was revealed that the waveform of the absorbance change reflects the behavior of the physical rotation. From the analysis of the waveform, it was experimentally found that the easy axis of the MNP aligns partially and oscillates with the small amplitude under an alternating magnetic field. The rotation mechanism of the MNP in liquids under an alternating magnetic field is proposed based on the observed waveform of the absorbance change. We also investigated the influences of the viscosity and the field frequency on the rotation behavior and confirmed that these results were consistent with the mechanism.It is important to understand the rotational behavior of magnetic nanoparticles (MNPs) in liquids under an alternating magnetic field for their successful application in biomedical fields. These applications include magnetic hyperthermia therapy and magnetic particle imaging. In particular, recent theoretical studies suggest that the physical rotation of MNP itself causes a significant change in the magnetization response of MNPs. However, because it is hard to distinguish the contribution of the physical rotation to the magnetization curve, its behavior under an alternating field has not been established to date. In this study, we measured the absorbance change of maghemite MNP suspension. We observed magnetically induced linear dichroism under a damped oscillatory magnetic field (DOMF) with Faraday configuration, where the propagation of light was parallel to the magnetic field. Accompanied by the application of DOMF, an absorbance change was observed. Through numerical simulations, it was revealed that...