Accuracy and reproducibility of CFD predicted wall shear stress using 3D ultrasound images
Accuracy and reproducibility of CFD predicted wall shear stress using 3D ultrasound images
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DOI：
10.1115/1.1553973
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发表时间：
2003-04-01
影响因子：
1.7
通讯作者：
Xu, XY
中科院分区：
文献类型：
--
作者：
Augst, AD;Barratt, DC;Xu, XY
计算流体动力学（CFD）流动模拟技术有可能提高我们对动脉粥样硬化中血流动力学因素的理解。最近，3D超声已经成为其他3D成像技术（如磁共振血管造影术（MRA））的替代品。该方法可用于生成适用于CFD模拟的真实血管几何形状。为了评估从图像采集到重建再到CFD模拟的过程的准确性和再现性，使用3D超声对人颈动脉分叉体模扫描三次。几何结构进行重建和流动模拟进行了三套，以及使用计算机辅助设计（CAD）从制造商给出的几何信息生成的模型上。结果发现，三个重建集显示出良好的再现性以及令人满意的定量协议与CAD模型。分析可能代表“最差情况”的两个选定位置，比较超声和CAD重建模型的准确性估计在最大瞬时WSS的7.2%和7.7%之间，比较三次扫描的再现性在其平均最大值的8.2%和10.7%之间。
Computational fluid dynamics (CFD) flow simulation techniques have the potential to enhance our understanding of how haemodynamic factors are involved in atherosclerosis. Recently, 3D ultrasound has emerged as an alternative to other 3D imaging techniques, such as magnetic resonance angiography (MRA). The method can be used to generate realistic vascular geometry suitable for CFD simulations. In order to assess accuracy and reproducibility of the procedure from image acquisition to reconstruction to CFD simulation, a human carotid artery bifurcation phantom was scanned three times using 3D ultrasound. The geometry was reconstructed and flow simulations were carried out on the three sets as well as on a model generated using computer aided design (CAD) from the geometric information given by the manufacturer It was found that the three reconstructed sets showed good reproducibility as well as satisfactory quantitative agreement with the CAD model. Analyzing two selected locations probably representing the 'worst cases,' accuracy comparing ultrasound and CAD reconstructed models was estimated to be between 7.2% and 7.7% of the maximum instantaneous WSS and reproducibility comparing the three scans to be between 8.2% and 10.7% of their average maximum.