Prevalence and clinical profile of pancreatic cancer-associated diabetes mellitus
Prevalence and clinical profile of pancreatic cancer-associated diabetes mellitus
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DOI：
10.1053/j.gastro.2008.01.039
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发表时间：
2008-04-01
期刊：
影响因子：
29.4
通讯作者：
Chari, Suresh T.
中科院分区：
文献类型：
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作者：
Pannala, Rahul;Leirness, Jeffery B.;Chari, Suresh T.
背景与目的：有关胰腺癌(PaQ)相关性糖尿病(DM)的临床资料有限。我们比较了有无PAC的受试者DM的患病率和临床特征。方法：我们前瞻性地招募了512例新诊断的PAC患者和933名年龄相近的对照组，他们完成了人口学和临床调查问卷，并在招募时和胰腺十二指肠切除术后测定了空腹血糖(FBG)水平(n=105)。空腹血糖水平为126 mg/dL或正在接受降糖治疗的受试者被归类为糖尿病。结果：DM的患病率较高(47%vs7%；P
Background & Aims: information on the clinical profile of pancreatic cancer (PaQ associated diabetes (DM) is limited. We compared the prevalence and clinical characteristics of DM in subjects with and without PaC. Methods: We prospectively recruited 512 newly diagnosed PaC cases and 933 controls of similar age, who completed demographic and clinical questionnaires and had fasting blood glucose (FBG) levels measured at recruitment and after pancreati-coduodenectomy (n = 105). Subjects with a FBG level > 126 mg/dL or who were on antidiabetic treatment were classified as having DM. Results: DM was more prevalent (47% vs 7%; P