Do illness characteristics and familial risk differ between women with anorexia nervosa grouped on the basis of personality pathology?
Do illness characteristics and familial risk differ between women with anorexia nervosa grouped on the basis of personality pathology?
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DOI：
10.1017/s0033291705006641
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发表时间：
2006-04-01
影响因子：
6.9
通讯作者：
Treasure, J
中科院分区：
文献类型：
--
作者：
Holliday, J;Landau, S;Treasure, J
背景鉴于基于人格的群体在饮食障碍（ED）中的潜在效用，以及缺乏在神经性厌食症（AN）个体的大样本中使用这种方法的研究。本研究旨在研究（1）终生AN女性患者的性格特征，以及（2）这些性格特征是否与临床症状或病因学变量相关。153名终生诊断为DSM-IV AN的女性完成了自我报告的人格病理维度评估（DAPP）。聚类分析用于确定基于个性的亚组。然后对临床和病因学变量进行聚类比较。三个基于人格的集群被确定，定义为广泛的，回避型和强迫型的人格病理。低反社会行为，高抑制和高强迫性的尺寸是共同的所有集群，而与情绪失调的尺寸出现更多的异质性。临床症状与人格特征无关，除了在广泛组中有更多禁食行为的趋势。极端人格特征范围最大的强迫性集群报告了最高的家族风险或饮食病理学。在我们的AN样本中确定的三个集群与之前在更广泛的饮食失调样本中确定的集群相似。基于个性的集群不符合整体的临床症状，但病因学差异支持其有效性。更广泛的人格病理指示情绪失调，身份和关系的问题，除了核心特征，可能会增加风险较低的人对AN的脆弱性。
Background. In view of the potential utility of personality-based groups in eating disorders (EDs), and the lack of studies using this approach in large samples of individuals with anorexia nervosa (AN). this study set out to examine (1) the nature of personality-based clusters of women with lifetime AN and (ii) if these clusters are associated with either clinical symptoms or aetiological variables.Method. The self-report Dimensional Assessment of Personality Pathology (DAPP) was completed by 153 women with a lifetime diagnosis of DSM-IV AN. A cluster analysis was used to identify personality-based subgroups. Clusters were then compared on clinical and aetiological variables.Results. Three personality-based clusters were identified, defined by broad, avoidant and compulsive types of personality pathology. Dimensions of low dissocial behaviour, high inhibition and high compulsivity were common to all clusters, while dimensions related to emotional dysregulation appeared more heterogeneous. Clinical symptoms were not related to personality profile With the exception of a trend towards more Fasting behaviour in the broad group. The compulsive cluster with the narrowest range of extreme personality traits reported the highest familial risk or eating pathology.Conclusions. The three clusters identified in our AN sample were similar to those previously identified in broader eating disordered samples. Personality-based clusters did not correspond overall to clinical symptoms but aetiological differences supported their validity. Broader personality pathology indicative of emotional dysregulation, problems with identity and relationships, in addition to core traits, may increase vulnerability to AN in those with less risk.