A fiber-optic-based multichannel time-correlated single-photon-counting device with subnanosecond time resolution

A fiber-optic-based multichannel time-correlated single-photon-counting device with subnanosecond time resolution
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具有亚纳秒时间分辨率的基于光纤的多通道时间相关单光子计数装置

DOI:
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发表时间:
1999
期刊:
影响因子:
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通讯作者:
S. Soper
S. Soper
中科院分区:
--
文献类型:
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作者:
E. Waddell;W. Stryjewski;S. Soper

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研制了一种基于光纤的多通道时间相关单光子计数装置。被动锁模的钛:蓝宝石激光器提供了12个独立的时间相关的单光子计数通道,其中三个单光子雪崩二极管探测器被用来分析从通道的荧光的激发源。单模光纤为激发光和荧光发射提供了通道。我们确定激发脉冲经历50 fs的时间扩展,0.2 nm的光谱扩展,并且保持接近变换限制。每个通道的平均仪器响应函数被确定为181 ps(半峰全宽)。一个代表性的近红外染料,四磺酸铝萘,荧光寿命被确定为3.08纳秒,使用这种基于光纤的多通道时间相关单光子计数装置。
A fiber-optic-based multichannel time-correlated single-photon-counting device with subnanosecond time resolution was developed. A passively mode-locked Ti:sapphire laser provided the excitation source for 12 separate time-correlated single-photon counting channels in which three single-photon avalanche diode detectors were used to analyze the fluorescence from the channels. Single-mode optical fibers provided the conduit for the excitation light as well as the fluorescence emission. We determined that the excitation pulses undergo a temporal spread of 50 fs, a spectral spread of 0.2 nm, and remained nearly transform limited. The average instrument response function of each channel was determined to be 181 ps (full width at half maximum). The fluorescence lifetime of a representative near-infrared dye, aluminum tetrasulfonated naphthalocyanine, was determined to be 3.08 ns using this fiber-optic-based multichannel time-correlated single-photon-counting device.
标记 DNA 引物的动态荧光寿命检测。
DOI: 10.1016/s0378-4347(97)00102-3
发表时间: 1997
期刊: Journal of chromatography. B, Biomedical sciences and applications
影响因子: --
作者:
Li,LC;He,H;Nunnally,BK;McGown,LB
通讯作者: McGown,LB
DOI: 10.1021/ac961281p
发表时间: 1997-07-01
影响因子: 7.4
作者:
Nunnally, BK;He, H;McGown, LB
通讯作者: McGown, LB