European Stroke Organisation (ESO) guidelines for the management of spontaneous intracerebral hemorrhage
European Stroke Organisation (ESO) guidelines for the management of spontaneous intracerebral hemorrhage
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DOI：
10.1111/ijs.12309
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发表时间：
2014-10-01
影响因子：
6.7
通讯作者：
Wagner, Markus
中科院分区：
文献类型：
--
作者：
Steiner, Thorsten;Al-Shahi Salman, Rustam;Wagner, Markus
背景在过去的十年中，脑出血（ICH）占全球所有卒中的9%-27%，早期病死率高，功能预后差。鉴于最近关于ICH管理的随机对照试验（RCT），欧洲中风组织（ESO）更新了其关于ICH管理的循证指南。方法由来自11个欧洲国家的24名研究人员组成的多学科写作委员会确定了20个与ICH管理相关的问题，并根据随机对照试验中的证据，使用建议分级评估，结果我们发现了中等质量到高质量的证据来支持在急性卒中单元管理急性ICH患者的强烈建议，避免对与抗血栓药物使用无关的急性ICH进行止血治疗，避免渐进式压缩袜，在不动患者中使用间歇性气动压缩，以降血压为二级预防。我们发现中等质量的证据支持强烈降低收缩压的微弱建议，
BackgroundIntracerebral hemorrhage (ICH) accounted for 9% to 27% of all strokes worldwide in the last decade, with high early case fatality and poor functional outcome. In view of recent randomized controlled trials (RCTs) of the management of ICH, the European Stroke Organisation (ESO) has updated its evidence-based guidelines for the management of ICH.MethodA multidisciplinary writing committee of 24 researchers from 11 European countries identified 20 questions relating to ICH management and created recommendations based on the evidence in RCTs using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.ResultsWe found moderate- to high-quality evidence to support strong recommendations for managing patients with acute ICH on an acute stroke unit, avoiding hemostatic therapy for acute ICH not associated with antithrombotic drug use, avoiding graduated compression stockings, using intermittent pneumatic compression in immobile patients, and using blood pressure lowering for secondary prevention. We found moderate-quality evidence to support weak recommendations for intensive lowering of systolic blood pressure to