Associations of Doctor-Diagnosed Asthma with Immigration Status, Age at Immigration, and Length of Residence in the United States in a Sample of Mexican American School Children in Chicago
Associations of Doctor-Diagnosed Asthma with Immigration Status, Age at Immigration, and Length of Residence in the United States in a Sample of Mexican American School Children in Chicago
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DOI：
10.3109/02770900903114572
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发表时间：
2009-01-01
影响因子：
1.9
通讯作者：
Persky, Victoria W.
中科院分区：
文献类型：
--
作者：
Eldeirawi, Kamal;McConnell, Rob;Persky, Victoria W.
目标.在美国的墨西哥裔美国人中，出生在美国的儿童患哮喘的比例高于墨西哥出生的同龄人。本研究的目的是检查医生诊断的哮喘与移民相关变量的关联，并调查这些关联是否可以用可能随着移民而变化的因素来解释。方法.我们调查了2,023名墨西哥裔学龄儿童的父母，并在调整潜在的混杂变量后，研究了哮喘与出生、移民年龄和在美国居住时间的关系。结果在多变量分析中，与墨西哥出生的同龄人相比，美国出生的儿童患哮喘的几率增加了2.42倍（95%置信区间[CI]：1.52-3.83）。在2岁之前搬到美国的墨西哥出生的参与者患哮喘的可能性几乎是在2岁以上搬到美国的墨西哥出生的儿童的两倍。此外，在美国居住10年或以上的墨西哥出生的参与者患哮喘的可能性是在美国居住不到10年的墨西哥出生的学生的2.37倍。这些关联不能用各种各样的因素来解释，例如婴儿期的居住地;接触动物/宠物;感染史，泰诺使用，以及婴儿期抗生素使用;母乳喂养;暴露于环境烟草烟雾;日托出勤率和兄弟姐妹的数量;以及语言使用。结论.我们的研究结果指出出生，移民年龄和在美国居住的时间对墨西哥裔美国儿童哮喘风险的影响，这表明随着移民而变化的潜在可改变因素可能与疾病有关。这项研究的结果应该刺激进一步的研究，以解释可能导致墨西哥裔美国人哮喘风险差异的因素。
Objectives. Among Mexican Americans in the United States, children who were born in the US had higher rates of asthma than their Mexico-born peers. The purpose of this study was to examine the associations of doctor-diagnosed asthma with immigration-related variables and to investigate whether these associations could be explained by factors that may change with migration. Methods. We surveyed parents of 2,023 school children of Mexican descent and examined the associations of asthma with nativity, age at immigration, and length of residence in the US after adjusting for potential confounding variables. Results. In multivariate analyses, US-born children had a 2.42-fold (95% confidence interval [CI]:1.52-3.83) increased odds of asthma compared with their Mexico-born peers. Mexico-born participants who moved to the US before 2 years of age were almost twice as likely to experience asthma compared with Mexico-born children who moved to the US >= 2 years of age. In addition, Mexico-born participants who lived in the US for 10 years or more were 2.37 times more likely to have asthma than Mexico-born students who lived in the US for less than 10 years. These associations were not explained by a wide variety of factors such as place of residence in infancy; exposure to animals/pets; history of infections, Tylenol use, and antibiotic use in infancy; breastfeeding; exposure to environmental tobacco smoke; daycare attendance and number of siblings; and language use. Conclusions. Our findings point to the effects of nativity, age at immigration, and duration of residence in the US on the risk of asthma in Mexican American children, suggesting that potentially modifiable factors that change with migration may be linked with the disease. The findings of this study should stimulate further research to explain factors that may be responsible for the observed differentials in the risk of asthma among Mexican Americans.