Cortical steady-state responses to central and peripheral auditory beats
Cortical steady-state responses to central and peripheral auditory beats
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DOI：
10.1093/cercor/bhm153
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发表时间：
2008-05-01
期刊：
影响因子：
3.7
通讯作者：
Pantev, Christo
中科院分区：
文献类型：
--
作者：
Draganova, Rossitza;Ross, Bernhard;Pantev, Christo
本文用500和540 Hz纯音、持续时间为1.0 s、起始时间为2.0 s的双耳和双耳两分刺激，研究了40 Hz听觉稳态反应（ASSR）的不同类型产生机制。当两个音调的总和同时呈现给双耳时，它们在耳蜗水平上相互作用，并导致被称为"外周搏动"的40 Hz搏动的感知。将500赫兹的音调分两耳给一只耳朵，将540赫兹的音调分两耳给另一只耳朵，这导致了作为中枢相互作用的结果的搏动感知，最有可能是在上级橄榄核中，并被称为"中枢搏动"。"ASSR和瞬态N1m反应在两种刺激条件下的平均151通道全头脑磁图记录中发现，并在两个半球中用单个时空等效电流偶极子建模。与N1m源相比，两种情况下的ASSR源更靠前，更靠下，更靠内侧。在两种刺激条件下，ASSR的磁场强度均呈右半球偏侧化。虽然中枢和外周搏动在听觉系统的不同水平上相互作用，但最初的反应是沿着传入听觉通路投射的，并激活共同的皮层来源。
Different types of generation mechanisms of 40-Hz auditory steady-state response (ASSR) were investigated using diotic and dichotic stimulation with 500- and 540-Hz pure tones of 1.0-s duration and 2.0-s stimulus onset asynchrony. When the sum of both tones was presented to both ears simultaneously, they interacted at cochlear level and resulted in perception of a 40-Hz beat termed "peripheral beat." Dichotic presentation of the 500-Hz tone to one ear and the 540-Hz tone to the other one resulted in beat perception as the effect of central interaction, most likely in the superior olivary nuclei and was termed "central beat." ASSR and transient N1m responses were found in the averaged 151-channel whole-head magnetoencephalographic recordings under both stimulus conditions and were modeled with single spatiotemporal equivalent current dipoles in both hemispheres. The ASSR sources in both conditions were more anterior, more inferior, and more medial compared with N1m sources. Right hemispheric lateralization of the magnetic field strength was found for the ASSR in both stimulus conditions. Although the central and peripheral beat interacted at different levels of the auditory system, the initial responses were projected along the afferent auditory pathway and activated common cortical sources.