The ABO and Lewis blood-group system. Immunochemistry, genetics and relation to human disease.
The ABO and Lewis blood-group system. Immunochemistry, genetics and relation to human disease.
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ABO 和 Lewis 血型系统。
DOI：
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发表时间：
1969
影响因子：
158.5
通讯作者：
D. Marcus
中科院分区：
文献类型：
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作者：
D. Marcus
尽管 ABO 和 Lewis 抗原在血型和输血中的重要性已得到公认，但很少有医生认识到该系统的非凡复杂性及其与人类疾病的关联。这些抗原存在于全身的分泌物中以及上皮细胞和内皮细胞的表面上。目前对肾移植的兴趣已将注意力转向肾血管内皮中的存在。母亲和胎儿之间的ABO血型不合可能会导致新生儿不孕或溶血病，并且某些血型的人患消化性溃疡或胃癌的可能性增加。本次审查的目的。 。 。
DESPITE the recognized importance of the ABO and Lewis antigens in blood typing and transfusion, few physicians appreciate the extraordinary complexity of this system and its association with human disease. These antigens are found in secretions throughout the body and on the surface of epithelial and endothelial cells. Current interest in kidney transplantation has directed attention to their presence in the renal vascular endothelium. ABO incompatibility between mother and fetus may produce infertility or hemolytic disease of the newborn, and persons of certain blood groups have an increased susceptibility to peptic ulcer or gastric cancer. The purpose of this review . . .