Organocatalytic asymmetric selenofunctionalization of tryptamine for the synthesis of hexahydropyrrolo[2,3-b]indole derivatives.
Organocatalytic asymmetric selenofunctionalization of tryptamine for the synthesis of hexahydropyrrolo[2,3-b]indole derivatives.
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DOI：
10.3762/bjoc.9.177
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发表时间：
2013
影响因子：
2.7
通讯作者：
Gong LZ
中科院分区：
文献类型：
--
作者：
Wei Q;Wang YY;Du YL;Gong LZ
色胺衍生物的手性磷酸催化的硒官能化提供了以高产率和合成有用水平的对映选择性（高达89%ee）获得3a-（苯硒基）-1，2，3，3a，8，8a-六氢吡咯并[2，3-B]吲哚衍生物的途径。
A chiral phosphoric acid-catalyzed selenofunctionalization of tryptamine derivatives provides access to 3a-(phenylselenyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole derivatives in high yields and with synthetically useful levels of enantioselectivity (up to 89% ee).