Mucociliary Flow in the Trachea during Anesthesia with Enflurane, Ether, Nitrous Oxide, and Morphine
Mucociliary Flow in the Trachea during Anesthesia with Enflurane, Ether, Nitrous Oxide, and Morphine
复制标题
安氟烷、乙醚、一氧化二氮和吗啡麻醉期间气管中的粘液纤毛流动
DOI：
10.1097/00132586-197712000-00033
复制
发表时间：
1977
期刊：
影响因子：
8.8
通讯作者：
R. W. Horrigan
中科院分区：
文献类型：
--
作者：
A. R. Forbes;R. W. Horrigan
在硫喷妥钠麻醉和安氟醚、乙醚和一氧化二氮-吗啡麻醉的不同情况下，用放射性液滴法测量了狗的气管粘膜纤毛流速。在0.6、1.2、1.8 MAC时，安氟醚产生剂量依赖性、可逆性的粘膜纤毛流抑制，与先前报道的氟烷相同。一氧化二氮-氟烷和一氧化二氮-吗啡在相同MAC水平下对粘膜纤毛流量的抑制程度与氟烷相同。在任何MAC水平下，乙醚均未明显抑制硫喷妥钠控制下的纤毛粘液流量。
Tracheal mucociliary flow rates in dogs were measured with a radioactive droplet technique during thiopental anesthesia, and subsequently during enflurane, ether, and nitrous oxide - morphine anesthesia on different occasions. Enflurane, at 0.6, 1.2,1.8 MAC, produced a dose-dependent, reversible depression of mucociliary flow equal to that previously reported for halothane. Nitrous oxide-halothane and nitrous oxide-morphine depressed mucociliary flow to the same extent as halothane at equivalent MAC levels. Ether did not depress mucociliary flow significantly from the thiopental control at any MAC level.