Associations between the exposure to persistent organic pollutants and type 2 diabetes in East China: A case-control study
Associations between the exposure to persistent organic pollutants and type 2 diabetes in East China: A case-control study
复制标题
华东地区持久性有机污染物暴露与2型糖尿病的关联：病例对照研究
DOI：
10.1016/j.chemosphere.2019.125030
复制
发表时间：
2020-02-01
期刊：
影响因子：
8.8
通讯作者：
Jiang, Guibin
中科院分区：
文献类型：
--
作者：
Han, Xu;Meng, Lingling;Jiang, Guibin
Persistent organic pollutants (POPs) have been associated with a high risk of type 2 diabetes in different regions, although few studies from China have been published. We aimed to investigate the associations between POP exposure and type 2 diabetes in Chinese population. A total of 158 participants diagnosed with type 2 diabetes and 158 participants without the disorder from Shandong Province were enrolled in this case-control study during 2016-2017. Nine polychlorinated biphenyl congeners (PCBs) and 2 polybrominated diphenyl ethers with detectable levels in >= 75% of the participants were selected for data analysis. The results showed that POP exposure was significantly and positively associated with the risk of diabetes after adjusting for age, sex, BMI, triglycerides and total cholesterol. However, we did not observe an obvious modified effect of adiposity on the associations between POP exposure and diabetes in the present study, as strong associations between POPs and diabetes were observed in both the higher-BMI (BMI >= 25 kg/m(2)) and the lower-BMI (BMI
