Rapid CO release from a Mn(I) carbonyl complex derived from azopyridine upon exposure to visible light and its phototoxicity toward malignant cells
Rapid CO release from a Mn(I) carbonyl complex derived from azopyridine upon exposure to visible light and its phototoxicity toward malignant cells
复制标题
DOI：
10.1039/c3cc46558f
复制
发表时间：
2013-01-01
影响因子：
4.9
通讯作者：
Mascharak, Pradip K.
中科院分区：
文献类型：
--
作者：
Carrington, Samantha J.;Chakraborty, Indranil;Mascharak, Pradip K.
合成并表征了两种Mn（I）羰基配合物[MnBr（azpy）（CO）（3）]和[Mn（azpy）（CO）（3）（PPh 3）]（ClO 4）（azpy = 2-苯基偶氮吡啶）。两种复合物在暴露于低功率可见光时均表现出快速的CO释放。[MnBr（azpy）（CO）（3）]对两种恶性肿瘤细胞系HeLa和MDA-MB-231显示出明显的光毒性。
Two Mn(I) carbonyl complexes namely [MnBr(azpy)(CO)(3)] and [Mn(azpy)(CO)(3)(PPh3)](ClO4) (azpy = 2-phenylazopyridine) have been synthesized and characterized. Both complexes exhibit rapid CO release upon exposure to low power visible light. [MnBr(azpy)(CO)(3)] shows significant phototoxicity toward two malignant cell lines HeLa and MDA-MB-231.