Quality of life after adenotonsillectomy for SDB in children

Quality of life after adenotonsillectomy for SDB in children
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DOI:
10.1016/j.otohns.2005.05.040
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发表时间:
2005-10-01
影响因子:
3.4
通讯作者:
Kelly, J
Kelly, J
中科院分区:
医学2区
文献类型:
--
作者:
Mitchell, RB;Kelly, J

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目的:评价睡眠呼吸紊乱综合征(SDB)相对严重程度与生活质量的关系,并比较人口学特征相近但患有阻塞性睡眠呼吸暂停综合征(OSAS)或SDB类型较轻的儿童行腺扁桃体切除术后生活质量的变化。研究设计与背景:所有研究参与者均接受多导睡眠图检查以记录SDB的严重程度。采用OSA-18生活质量调查问卷(OSA-18)评价扁桃体切除术缓解SDB的疗效。采用重复测量方差分析比较两组患儿(OSAS组和轻度SDB组)手术前后的OSA-18评分。以术前评分为协变量,用协方差分析比较两组间的变化。结果:研究对象包括61名儿童,43名OSAS和18名轻度SDB。两组人群的人口学特征相似。OSAS儿童的平均呼吸暂停低通气指数为21(范围5-46),轻度SDB儿童的平均呼吸暂停低通气指数为3(范围0-4.9)。两组患儿术后OSA-18总分及各领域评分均有明显改善(P
OBJECTIVE: To evaluate the relationship between quality of life and the relative severity of sleep-disordered breathing (SDB) and to compare changes in quality of life after adenotonsillectomy in children with similar demographics but with either obstructive sleep apnea syndrome (OSAS) or with milder forms of SDB.STUDY DESIGN AND SETTING: All study participants underwent polysomnography to document the severity of SDB. The effectiveness of adenotonsillectomy for the relief of SDB was evaluated by using the OSA-18 quality of life survey (OSA-18). Preoperative and postoperative OSA-18 scores for each group of children (OSAS and mild SDB) were compared by using a repeated measures ANOVA. Changes between the 2 groups were compared by using an analysis of covariance with the preoperative score as a covariate.RESULTS: The study population included 61 children, 43 with OSAS and 18 with mild SDB. The demographics in the 2 groups were similar. The mean apnea-hypopnea index for children with OSAS was 21 (range, 5-46), and for children with mild SDB, it was 3 (range 0-4.9). The total OSA-18 score and the scores for all domains showed significant improvement after surgery for both groups of children (P