One Thousand Two Hundred Ninety Nuclear Genes from a Genome-Wide Survey Support Lungfishes as the Sister Group of Tetrapods
One Thousand Two Hundred Ninety Nuclear Genes from a Genome-Wide Survey Support Lungfishes as the Sister Group of Tetrapods
复制标题
全基因组调查中的一千二百九十个核基因支持肺鱼是四足动物的姐妹群
DOI：
10.1093/molbev/mst072
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发表时间：
2013-08-01
影响因子：
10.7
通讯作者：
Zhang, Peng
中科院分区：
文献类型：
--
作者：
Liang, Dan;Shen, Xing Xing;Zhang, Peng
脊椎动物脊椎动物的脊椎动物发生史中唯一尚未解决的部分涉及腔棘鱼、肺鱼和四足动物之间的关系。尽管在过去的三十年里对这个问题进行了积极的研究，但仍然很难在统计上确定肺鱼单独或肺鱼和腔棘鱼一起与四足动物密切相关。为了解决这一争议，我们通过分析现有的基因组和转录组数据，组装了一个包含1，290个核基因的数据集，编码690，838个氨基酸残基。系统发育分析的这一数据集提供了压倒性的证据，肺鱼是最近的生活亲属的陆地脊椎动物。这一结果得到了最大似然法和最大简约法分析、CAT模型分析的贝叶斯后验概率和拓扑检验的高自举值的有力支持。此外，没有数据拼接的物种树分析也强烈支持这一结果。
The only currently unresolved portion of the backbone phylogeny of the vertebrates involves the relationships among coelacanths, lungfishes, and tetrapods. Despite active research on this question over the past three decades, it is still difficult to determine statistically whether lungfishes alone or both lungfishes and coelacanths together are closely related to tetrapods. To resolve this controversy, we assembled a data set comprising 1,290 nuclear genes encoding 690,838 amino acid residues by analyzing available genome and transcriptome data. Phylogenetic analyses of this data set provided overwhelming evidence that the lungfishes are the closest living relatives of the land vertebrates. This result is strongly supported by high bootstrap values from maximum likelihood and maximum parsimony analyses, Bayesian posterior probabilities of CAT model analysis, and topological tests. Additionally, a species tree analysis without data concatenation also strongly supported this result.