PRIMARY CARDIAC LEIOMYOSARCOMAS
PRIMARY CARDIAC LEIOMYOSARCOMAS
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DOI：
10.1016/0003-4975(91)91031-p
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发表时间：
1991-06-01
影响因子：
4.6
通讯作者：
REBELO, LS
中科院分区：
文献类型：
--
作者：
ANTUNES, MJ;VANDERDONCK, KM;REBELO, LS
描述了两名原发性心脏平滑肌肉瘤患者，这是心脏最罕见的恶性肿瘤之一。 第一位患者患有肺干肿瘤，入院时出现提示肺血栓栓塞的症状。 第二例患者左心房有肿瘤，并有二尖瓣阻塞和反流的体征和症状。 2名患者接受了手术，随后接受了辅助化疗。 两人均在术后 22 个多月后死亡，并需要多次入院治疗与病理学或原发性心脏平滑肌肉瘤治疗相关的并发症。 尽管如此，积极的手术切除和化疗似乎提高了这些原发性心脏平滑肌肉瘤患者的生存率，因为他们是报道的存活时间最长的人之一。
Two patients with primary cardiac leiomyosarcoma, one of the rarest malignant tumors of the heart, are described. The first patient had a tumor of the pulmonary trunk and was admitted with symptoms suggestive of pulmonary thromboembolism. The second had a tumor of the left atrium and had signs and symptoms of mitral valve obstruction and regurgitation. The 2 patients were operated on and later underwent adjuvant chemotherapy. Both died more than 22 months after operation, having required multiple hospital admissions for treatment of complications related to the pathology or the treatment of the primary cardiac leiomyosarcoma. Nonetheless, aggressive surgical excision followed by chemotherapy appears to have improved survival in these patients with primary cardiac leiomyosarcoma, as they are among the longest survivors reported.