Improved infarction rates in fibroids after the introduction of contrast-enhanced ultrasound during uterine artery embolization
Improved infarction rates in fibroids after the introduction of contrast-enhanced ultrasound during uterine artery embolization
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DOI：
10.1258/ar.2011.110331
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发表时间：
2012-02-01
期刊：
影响因子：
1.3
通讯作者：
Ring, Eva
中科院分区：
文献类型：
--
作者：
Dorenberg, Eric J.;Hol, Per-Kristian;Ring, Eva
背景资料：为了达到持续的症状控制和减少复发的风险，子宫动脉栓塞术（UAE）的目标应该是所有肌瘤的完全梗死。目的：回顾性评估在我们机构的UAE手术中引入造影剂增强超声（CEUS）后接受子宫动脉栓塞术（UAE）的患者的子宫肌瘤梗死率。材料和方法：纳入了2006年2月至2009年8月期间接受UAE治疗的30例患者。对术前、术后3个月和12个月获得的MR图像进行了审查。我们评估了每例患者主要肌瘤的体积变化以及所有肌瘤的梗死率。通过回顾病历对临床结果进行评价。该研究被批准的机构review board.Results：CEUS在技术上成功地进行了UAE过程中的所有患者。在5例病例中，根据CEUS结果调整了栓塞终点。主要肌瘤的平均体积收缩率在3个月后为39.8%，在12个月后为59.8%。在3个月和12个月时，97%的患者的所有纤维瘤组织完全梗死。没有重大并发症observed.Conclusion：在我们的机构UAE程序中引入CEUS后，实现了高梗死率。
Background: In order to achieve sustained symptom control and minimize the risk of recurrence, uterine artery embolization (UAE) should aim at complete infarction of all fibroids.Purpose: To retrospectively evaluate the infarction rate of uterine fibroids in patients that had undergone uterine artery embolization (UAE) after the introduction of contrast-enhanced ultrasound (CEUS) during UAE procedures at our institution.Material and Methods: Thirty patients treated with UAE between February 2006 and August 2009 were included. MR images obtained before, at 3 months, and 12 months after the procedure were reviewed. We evaluated volume changes in dominant fibroids as well as the infarction rate of all fibroids in each patient. Clinical results were evaluated by reviewing the medical records. The study was approved by the institutional review board.Results: CEUS was technically successfully performed during the UAE procedure in all patients. In five cases the endpoint of embolization was adjusted based on findings at CEUS. The mean volume shrinkage of dominant fibroids was 39.8% after 3 months and 59.8% after 12 months. There was complete infarction of all fibroid tissue in 97% of patients at 3 months and 96% at 12 months. No major complications were observed.Conclusion: After the introduction of CEUS during UAE procedures in our institution, high infarction rates were achieved.