Skin metastases in metastatic uveal melanoma: GNAQ/GNA11 mutational analysis as a valuable tool
Skin metastases in metastatic uveal melanoma: GNAQ/GNA11 mutational analysis as a valuable tool
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DOI：
10.1111/bjd.12291
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发表时间：
2013-07
影响因子：
10.3
通讯作者：
A. Tsianakas;Markus Böhm;V. Getova;D. Metze;N. Eter;T. Spieker;A. Bräuninger;T. Luger;M. Schiller;C. Sunderkötter
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文献类型：
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作者：
A. Tsianakas;Markus Böhm;V. Getova;D. Metze;N. Eter;T. Spieker;A. Bräuninger;T. Luger;M. Schiller;C. Sunderkötter
葡萄膜黑色素瘤占所有黑色素瘤的3.1%，具有高达50%的转移性疾病的高可能性，其中中位生存时间为6个月。虽然肝转移占主导地位的原发部位转移，原发性皮肤转移的存在仍在讨论中，但只有少数研究报告。
Uveal melanomas represent 3·1% of all melanomas, with a high potential of metastatic disease of up to 50%, where the median survival time is 6 months. Though liver metastases dominate as the primary site for metastasis, the existence of primary skin metastases is still under discussion but has been reported in only a few studies.