Travel-related health problems in the immunocompromised traveller: An exploratory study
Travel-related health problems in the immunocompromised traveller: An exploratory study
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DOI：
10.1016/j.tmaid.2018.05.005
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发表时间：
2018-09-01
影响因子：
12
通讯作者：
Grobusch, Martin P.
中科院分区：
文献类型：
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作者：
van Aalst, Marielle;van Ruissen, Marella C. E.;Grobusch, Martin P.
背景：免疫功能低下的旅行者（ICT）面临着与旅行相关的健康问题的风险增加。因此，建议他们前往专门的旅行前诊所，获得有关疫苗接种、疟疾化学预防和按需抗生素的建议。然而，研究产生相互矛盾的数据，关于旅行相关的健康问题所遇到的信息通信技术;质疑的理由，某些建议，特别是按需抗生素的意见。Objective：为了评估自我报告的旅行相关的健康问题，抗生素的使用，医疗访问和风险行为的信息通信技术和controls.Methods：我们进行了一项基于实验室的观察性研究与试点字符。我们从旅行前诊所招募了参与者。旅行后2-4周进行电话采访，采用结构化questionnaire.Results：我们包括30个ICT和30个对照。报告与旅行有关的健康问题、抗生素使用和就医的信通技术组多于对照组，尽管在统计上不显著。在信通技术中，旅行者的腹泻似乎更为严重。此外，1名信通技术人员在旅行后因肺炎住院。在信通技术中，2/30（7%）使用了按需抗生素，但没有指示（根据荷兰国家旅行建议协调中心的协议或医生处方）。Reflections，6/30（20%）没有使用按需抗生素，而实际上表明根据本protocol.Discussion：我们的研究结果证实了按需抗生素的建议。然而，信通技术往往不能正确使用按需抗生素;因此，它们需要非常仔细的指导。
Background: Immunocompromised travellers (ICTs) are at increased risk of travel-related health problems. Therefore, they are advised to attend specialised pre-travel clinics for advice on vaccination, malaria chemoprophylaxis and on-demand antibiotics. However, studies yield conflicting data regarding travel-related health problems encountered by ICTs; questioning the rationale for certain advices, and particularly the advice of on-demand antibiotics.Objective: To evaluate self-reported travel-related health problems, antibiotic use, medical visits and risk behaviours in ICTs and controls.Methods: We conducted a questionnaire-based observational study with pilot character. We recruited participants from a (medical) pre-travel clinic. Telephone interviews were conducted 2-4 weeks post-travelling, applying a structured questionnaire.Results: We included 30 ICTs and 30 controls. More ICTs than controls reported travel-related health problems, antibiotic use and medical visits, although not statistically significant. Travellers' diarrhoea appeared to be more severe in ICTs. Furthermore one ICT was hospitalized post-travel due to pneumonia. Of ICTs, 2/30 (7%) used on demand antibiotics while not indicated (according to the protocol of the Dutch national coordinating centre for travel advice or prescribed by a physician). Reversely, 6/30 (20%) did not use on demand antibiotics while actually indicated according to this protocol.Discussion: Our findings substantiate the recommendation of on demand antibiotics. However, ICTs did often not use on demand antibiotics correctly; they therefore need very careful instructions.