Development and pilot-testing of a psoriasis screening tool
Development and pilot-testing of a psoriasis screening tool
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DOI：
10.1111/j.1365-2133.2009.09247.x
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发表时间：
2009-10-01
影响因子：
10.3
通讯作者：
Qureshi, A. A.
中科院分区：
文献类型：
--
作者：
Dominguez, P. L.;Assarpour, A.;Qureshi, A. A.
背景有必要验证银屑病自我报告的流行病学研究，其中个人可能不会看到皮肤科医生或其他health care providers.Objectives的开发和试点测试的银屑病筛查工具（PST）在门诊setting.Patients和方法PST设计了8个封闭式的问题，需要一个“是”或“否”的反应。银屑病的皮肤、指甲和头皮变化的典型图像包括相应的问题。我们对222名在皮肤科诊所就诊的连续个体进行了PST。所有讲英语的受试者都在没有帮助的情况下完成了PST。一个委员会认证的皮肤科医生建立了银屑病的诊断或排除银屑病在所有participated.Results共222完成PST问卷进行分析。银屑病组有111人，非银屑病组有111人。三个问题的组合导致银屑病的敏感性为96.4%[95%置信区间（CI）93.2 - 98.0]，特异性为97.3%（95% CI 94.1 - 98.9）。添加图片问题使筛选工具的灵敏度增加至98.2%（95% CI 95.0 - 99.5）。在111名银屑病患者中，69%的人对斑块型银屑病的回答是肯定的，50%的人对指甲受累的回答是肯定的，66%的人对头皮受累的回答是肯定的，59%的人回答是有反型银屑病。结论这项初步研究表明，PST可以区分银屑病患者和非银屑病患者，在一家皮肤科门诊部就诊的人群中。此外，PST可用于鉴定银屑病表型。尽管在这项试点研究中，PST可能受到谱偏差的限制，但我们相信它仍然是收集偏远人群银屑病信息的可靠工具。
Background There is a need to validate psoriasis self-reports in epidemiological studies, where individuals may not be seeing dermatologists or other health care providers.Objectives To develop and pilot test the Psoriasis Screening Tool (PST) in an ambulatory setting.Patients and methods The PST was designed with eight closed-ended questions requiring a 'yes' or 'no' response. Typical images of skin, nail and scalp changes in psoriasis were included with respective questions. We administered the PST to 222 consecutive individuals being seen at a dermatology clinic. All English-speaking subjects completed the PST without assistance. A board-certified dermatologist established the diagnosis of psoriasis or excluded psoriasis in all participants.Results A total of 222 completed PST questionnaires were included for analysis. There were 111 individuals in the psoriasis group and 111 individuals in the nonpsoriasis group. A combination of three questions resulted in a sensitivity of 96.4% [95% confidence interval (CI) 93.2-98.0] and specificity of 97.3% (95% CI 94.1-98.9) for psoriasis. Adding a pictorial question increased the sensitivity of the screening tool to 98.2% (95% CI 95.0-99.5). Of the 111 individuals with psoriasis, 69% answered yes to having plaque-type psoriasis, 50% answered yes to having nail involvement, 66% answered yes to having scalp involvement, and 59% answered yes to having inverse-type psoriasis.Conclusions This pilot study suggests that the PST can distinguish individuals with psoriasis from individuals without psoriasis in an English-speaking population being seen at an outpatient dermatology clinic. Furthermore, the PST may be used to identify psoriasis phenotypes. Although the PST may be limited by spectrum bias in this pilot study, we believe it remains a reliable tool to collect information on psoriasis in remote populations.