Mechanistic insights into transient severe mitral regurgitation
Mechanistic insights into transient severe mitral regurgitation
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短暂性严重二尖瓣反流的机制见解
DOI：
10.3109/17482941.2015.1110243
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
S. Pislaru
中科院分区：
文献类型：
--
作者：
J. Liang;F. Syed;A. Killu;B. Boilson;R. Nishimura;S. Pislaru
急性二尖瓣反流（AMR）是一种已知的急性冠状动脉综合征并发症，通常与后乳头肌功能障碍/破裂有关。在严重的情况下，AMR的管理需要手术干预。在没有左室收缩功能障碍和冠状动脉狭窄的患者中，可逆性严重AMR可能是由引起心内膜下短暂缺血的过程引起的，如间歇性低血压或冠状动脉血管痉挛。我们报告了两例由于心内膜下和/或心内膜缺血引起的可逆性短暂性AMR，这两例病例都对短暂性严重AMR的机制提供了深入的了解。
Acute mitral regurgitation (AMR), a known complication of acute coronary syndromes, is usually associated with posterior papillary muscle dysfunction/rupture. In severe cases, management of AMR requires surgical intervention. Reversible severe AMR in patients in the absence of left ventricular systolic dysfunction and coronary artery stenosis may result from processes which cause transient subendocardial ischemia, such as intermittent episodes of hypotension or coronary artery vasospasm. We present two cases of reversible transient AMR due to subendocardial and/or endocardial ischemia, both of which offer insight into the mechanism of transient severe AMR.