Launching a multidisciplinary European collaboration towards a cure for HIV: The EU2Cure Consortium.
Launching a multidisciplinary European collaboration towards a cure for HIV: The EU2Cure Consortium.
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DOI：
10.1016/j.jve.2021.100045
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发表时间：
2021-06
影响因子：
5.5
通讯作者：
Boucher CAB
中科院分区：
文献类型：
--
作者：
Rokx C;Prins HAB;Vandekerckhove L;Fidler SJ;Frater J;Bracchi M;Søgaard OS;Tolstrop M;Rasmussen TA;Salgado M;Blanco J;Martinez-Picado J;Clotet B;Tambussi G;Groenendijk A;Verbon A;Boucher CAB
我们感到迫切需要启动EU2Cure联盟，通过加强欧洲内部的合作，支持研究并找到治疗人类免疫缺陷病毒（HIV）感染的方法。该联盟向来自学术界和社区的欧洲治疗利益相关者开放，以建立联系。该联盟的目的是加强欧洲艾滋病毒治疗团体和社区之间的研究合作，并促进与其他学术和社区治疗联盟、私人团体和决策者之间的互动。我们的主要目标是创建一个欧洲研究议程，数据共享，并为临床和转化科学开发最佳实践，以实现临床可行的艾滋病毒治愈策略的突破。该联盟还应使更广泛的艾滋病毒感染者群体能够开展合作研究。除了储层研究，我们已经确定了三个重叠的科学兴趣，为欧洲网络的进一步研究提供了起点：开发“休克和杀死”治疗策略，定义HIV治愈生物标志物，连接治疗队列。这一战略应有助于利益攸关方保持艾滋病毒治疗研究方面的进展，无论全球卫生或政治危机是否同时发生。
We felt the urgency to launch the EU2Cure Consortium to support research and find a cure for the human immunodeficiency virus (HIV) infection through intensified collaboration within Europe. This consortium is open to stakeholders on cure in Europe from academia and the community to connect. The aim of this consortium is to intensify the research collaboration amongst European HIV cure groups and the community and facilitate interactions with other academic and community cure consortia, private parties, and policy makers. Our main aim is to create a European research agenda, data sharing, and development of best practice for clinical and translational science to achieve breakthroughs with clinically feasible HIV cure strategies. This consortium should also enable setting up collaborative studies accessible to a broader group of people living with HIV. Besides reservoir studies, we have identified three overlapping scientific interests in the consortium that provide a starting point for further research within a European network: developing “shock and kill” cure strategies, defining HIV cure biomarkers, and connecting cure cohorts. This strategy should aid stakeholders to sustain progress in HIV cure research regardless of coincidental global health or political crises.
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影响因子：
16.6
作者：
Hurst J;Hoffmann M;Pace M;Williams JP;Thornhill J;Hamlyn E;Meyerowitz J;Willberg C;Koelsch KK;Robinson N;Brown H;Fisher M;Kinloch S;Cooper DA;Schechter M;Tambussi G;Fidler S;Babiker A;Weber J;Kelleher AD;Phillips RE;Frater J
通讯作者：
Frater J
DOI：
10.1016/s2352-3018(20)30234-4
发表时间：
2021-01
期刊：
The lancet. HIV
影响因子：
--
作者：
Lewin SR;Attoye T;Bansbach C;Doehle B;Dubé K;Dybul M;SenGupta D;Jiang A;Johnston R;Lamplough R;McCune JM;Nabel GJ;Ndung'u T;Pottage J;Ripin D;Rooney JF;Sikazwe I;Nsubuga M;Warren M;Deeks SG;Sunnylands 2019 Working Group
通讯作者：
Sunnylands 2019 Working Group
原发性HIV感染中的短期抗逆转录病毒疗法。
DOI：
10.1056/nejmoa1110039
发表时间：
2013-01-17
期刊：
The New England journal of medicine
影响因子：
--
作者：
SPARTAC Trial Investigators;Fidler S;Porter K;Ewings F;Frater J;Ramjee G;Cooper D;Rees H;Fisher M;Schechter M;Kaleebu P;Tambussi G;Kinloch S;Miro JM;Kelleher A;McClure M;Kaye S;Gabriel M;Phillips R;Weber J;Babiker A
通讯作者：
Babiker A
影响因子：
11.1
作者：
Stoszko M;De Crignis E;Rokx C;Khalid MM;Lungu C;Palstra RJ;Kan TW;Boucher C;Verbon A;Dykhuizen EC;Mahmoudi T
通讯作者：
Mahmoudi T
影响因子：
16.1
作者：
Rasmussen, Thomas A.;Tolstrup, Martin;Sogaard, Ole S.
通讯作者：
Sogaard, Ole S.