Diet and exercise weight-loss trial in lactating overweight and obese women
Diet and exercise weight-loss trial in lactating overweight and obese women
复制标题
DOI：
10.3945/ajcn.112.040196
复制
发表时间：
2012-10-01
影响因子：
7.1
通讯作者：
Winkvist, Anna
中科院分区：
文献类型：
--
作者：
Bertz, Fredrik;Brekke, Hilde K.;Winkvist, Anna
背景：目前的证据表明，饮食和运动联合治疗产后体重减轻。然而，据我们所知，它们的单独和相互作用以及长期结果都没有得到评估。目的：我们评估12周饮食行为改变(D)治疗减少能量摄入，体育锻炼行为改变(E)治疗实施适度有氧运动，或与对照组（常规护理）(C)相比，饮食和体育锻炼行为改变（DE）联合治疗是否降低了哺乳期妇女在治疗结束时和治疗结束后9个月1年随访时的体重。设计：在产后10-14周，68名孕前体重指数（kg/m(2)）为25-35的瑞典哺乳期妇女被随机分为D、E、DE和C组。测量分别在基线、干预后进行，并在9个月后进行1年随访。采用2 × 2因子法分析各处理的主要效应和相互作用。结果：D组干预后及随访1年体重变化分别为-8.3 +/- 4.2和-10.2 +/- 5.7 kg；E组分别为-2.4 +/- 3.2和-2.7 +/- 5.9 kg；DE组分别为-6.9 +/- 3.0和-7.3 +/- 6.3 kg；C组分别为-0.8 +/- 3.0和-0.9 +/- 6.6 kg。D组对体重的主要影响显著（P < 0.001），而E组对体重的影响不显著（P < 0.001）。结论：饮食治疗为产后哺乳期妇女提供了临床相关的体重减轻，并在治疗后9个月持续。与单独饮食治疗相比，联合治疗没有产生显著的体重或身体组成变化。该试验在clinicaltrials.gov注册为NCT01343238。中华临床医学杂志，2012;16(6):591 - 591。
Background: Current evidence suggests a combined treatment of postpartum weight loss of diet and exercise. However, to our knowledge, neither their separate and interactive effects nor long-term outcomes have been evaluated.Objective: We evaluated whether a 12-wk dietary behavior modification (D) treatment to decrease energy intake, physical exercise behavior modification (E) treatment to implement moderate aerobic exercise, or combined dietary and physical exercise behavior modification (DE) treatment compared with control (usual care) (C) reduces body weight in lactating women measured at the end of treatment and at a 1-y follow-up 9 mo after treatment termination.Design: At 10-14 wk postpartum, 68 lactating Swedish women with a prepregnancy BMI (in kg/m(2)) of 25-35 were randomly assigned to D, E, DE, or C groups. Measurements were made at baseline, after the intervention, and again at a 1-y follow-up 9 mo later. A 2 x 2 factorial approach was used to analyze main and interaction effects of treatments.Results: Weight changes after the intervention and 1-y follow-up were -8.3 +/- 4.2 and -10.2 +/- 5.7 kg, respectively, in the D group; -2.4 +/- 3.2 and -2.7 +/- 5.9 kg, respectively, in the E group; -6.9 +/- 3.0 and -7.3 +/- 6.3 kg, respectively, in the DE group; and -0.8 +/- 3.0 and -0.9 +/- 6.6 kg, respectively, in the C group. The main effects of D treatment, but not of E treatment, on weight were significant at both times (P < 0.001).Conclusions: Dietary treatment provided clinically relevant weight loss in lactating postpartum women, which was sustained at 9 mo after treatment. The combined treatment did not yield significant weight or body-composition changes beyond those of dietary treatment alone. This trial was registered at clinicaltrials.gov as NCT01343238. Am J Clin Nutr 2012;96:698-705.