THE THALAMOSTRIATAL PROJECTION IN THE CAT
THE THALAMOSTRIATAL PROJECTION IN THE CAT
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DOI：
10.1002/cne.902230302
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发表时间：
1984-01-01
影响因子：
2.5
通讯作者：
BECKSTEAD, RM
中科院分区：
文献类型：
--
作者：
BECKSTEAD, RM
在单个丘脑核沉积3h -氨基酸后，用放射自显影法和小麦胚芽结合的山萝卜过氧化物酶沉积后的逆行细胞标记法，研究了从层内核和其他丘脑核到尾状核（CD）、壳核（PU）、伏隔核（Acc）和嗅结节（to）的突起组织。所有的吻侧板内核，包括中央外侧核（CL）、中央旁核（PC）、中央内侧核（CeM）和菱形核（Rh），都投射到纹状体。与吻侧板内群密切相关的突起来自室旁核（PV）细胞和髓纹外侧区域。这些核大致在中背核周围形成一个环，以一种非常特殊但松散的地形模式投射到纹状体的所有部分。位于Rh、PV内侧和沿髓纹的细胞主要向Acc和CD内侧投射；CL的背外侧细胞主要投射到CD和PU的背外侧；PC和CeM的细胞逐渐向CD和PU的腹侧和内侧以及Acc的外侧投射。在这个来自吻侧板内区域的投影上叠加的是来自尾侧板内群的投影，包括中央核（CM）、束旁核（PF）和束旁核（subPF）。这些核一起以松散但有特殊组织的地形投射到整个纹状体。CD和PU的外侧和背侧部分主要接受CM的纤维。CD、PU、Acc的腹内侧部分主要接受PF纤维；TO接收来自PF下部和PF腹侧部分的纤维，丘脑外侧核团中的几个核也投射到纹状体的特定部分。腹侧前核的喙内侧部分细胞向CD头突出，腹侧核的喙侧部分细胞向CD头和PU头突出。分散在后核复合体外侧的几个细胞向头外侧投射，后核复合体内侧细分的吻侧延伸部分的细胞向头和体外侧投射。膜旁核的几个细胞选择性地向Acc投射。猫的整个丘脑纹状体投影的详细地图，因此，提供了关于这个知之甚少的系统的更具体的功能问题的基础。
The organization of the projections from the intralaminar and other thalamic nuclei to the caudate nucleus (CD), putamen (PU), nucleus accumbens (Acc) and olfactory tubercle (TO) were examined in the cat by autoradiography after deposits of 3H-amino acids in individual thalamic nuclei and by retrograde cell labeling after intrastriatal deposits of wheat-germ-conjugated horseradish peroxidase. All of the rostral intralaminar nuclei, considered to include the central lateral (CL), paracentral (PC), central medial (CeM), and rhomboid nuclei (Rh), project to the striatum. Projections closely associated with those of the rostral intralaminar group arise from cells of the paraventricular nucleus (PV) and a region lateral to the stria medullaris. These nuclei, which roughly form a ring around the mediodorsal nucleus, project in a highly particular, but loosely arranged topographic pattern to all parts of the striatum. The medially located cells in Rh, PV and those alongside the stria medullaris project mainly to medial parts of Acc and CD; the dorsolaterally located cells of CL project mainly to the dorsolateral parts of CD and PU; cells in PC and CeM project to progressively more ventral and medial parts of CD and PU, and the lateral part of Acc. Superimposed on this projection from the rostral intralaminar region is the projection from the caudal intralaminar group including the centromedian (CM), parafascicular (PF) and subparafascicular nuclei (subPF). Together these nuclei project in a loosely but specifically organized topography to the entire striatum. The lateral and dorsal parts of CD and PU receive fibers mainly from CM. Ventral and medial parts of CD and PU and Acc receive fibers mainly from PF; TO receives fibers from subPF and the ventral part of PF. Several nuclei in the lateral nuclear mass of the thalamus also project to particular parts of the striatum. Cells in the rostromedial part of the ventral anterior nucleus project to the head of CD and some cells in the rostral part of the ventromedial nucleus project to the head of CD and to PU. Several cells scattered in the lateral posterior complex project to lateral parts of the head of CD, and cells in the rostral extension of the medial subdivision of the posterior nuclear complex project to lateral parts of the head and body of CD. Several cells of the paratenial nucleus project selectively to Acc. A detailed map of the total thalamostriatal projection in the cat and, hence, a basis for more specific functional questions about this poorly understood system is provided.