Randomized trial of busulfan vs total body irradiation containing conditioning regimens for children with acute lymphoblastic leukemia:: A Pediatric Blood and Marrow Transplant Consortium study

Randomized trial of busulfan vs total body irradiation containing conditioning regimens for children with acute lymphoblastic leukemia:: A Pediatric Blood and Marrow Transplant Consortium study
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DOI:
10.1038/sj.bmt.1704198
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发表时间:
2003-09-01
影响因子:
4.8
通讯作者:
Simms, S
Simms, S
中科院分区:
医学3区
文献类型:
--
作者:
Bunin, N;Aplenc, R;Simms, S

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急性淋巴细胞白血病儿童的预处理方案通常包括全身照射(TBI),这可能会导致严重的后遗症。本研究的主要目的是评估接受白消安(Bu)或TBI方案的异基因干细胞移植(SCT)的ALL儿童的结局。患者
Conditioning regimens for children with ALL have generally included total body irradation (TBI), which may result in significant sequelae. The primary aim of this study was to evaluate the outcome for children with ALL undergoing allogeneic stem cell transplant (SCT) with either busulfan (Bu) or TBI regimens. Patients