Usefulness of induced sputum and fibreoptic bronchoscopy specimens in the diagnosis of pulmonary tuberculosis
Usefulness of induced sputum and fibreoptic bronchoscopy specimens in the diagnosis of pulmonary tuberculosis
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DOI：
10.1177/147323000503300215
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发表时间：
2005-03-01
影响因子：
1.6
通讯作者：
Aktas, E
中科院分区：
文献类型：
--
作者：
Saglam, L;Akgun, M;Aktas, E
我们探讨了诱导痰(IS)和支气管灌洗(BL)标本对自然痰阴性或不能自发产生痰的疑似肺结核患者的诊断价值。用纤维支气管镜对55例患者的IS和BL标本进行抗酸杆菌(AFB)检测和结核分枝杆菌培养。IS涂片阳性23例，BL涂片阳性26例，IS或BL培养阳性42例。B细胞培养较IS、B L涂片或IS标本培养具有更高的敏感性。细菌培养阳性的敏感率最高(86%)。对于早期诊断(IS或BL涂片阳性)，敏感性为57%。与自然痰相比，纤维支气管镜检查具有更高的敏感性，当自然痰或诱导痰中未检出AFB时，纤维支气管镜检查有助于结核病的早期诊断。
We investigated the diagnostic value of induced sputum (IS) and bronchial lavage (BL) specimens in patients with suspected pulmonary tuberculosis who had negative spontaneous sputum specimens or who were unable to produce sputum spontaneously. IS specimens and BL specimens obtained using flexible fibreoptic bronchoscopy from 55 patients were evaluated for the presence of acid-fast bacilli (AFB) and cultured for Mycobacterium tuberculosis. Positive results were found with IS smear in 23 patients, BL smear in 26 patients, and IS or BL culture in 42 patients. Culture of BL specimens had a higher sensitivity than IS or BL smears or culture of IS specimens. The highest sensitivity rate was obtained with a positive BL or IS culture (86%). For early diagnosis (a positive IS or BL smear), the sensitivity was 57%. IS has a higher sensitivity rate than spontaneous sputum for the detection of tuberculosis, and fibreoptic bronchoscopy is useful for the early diagnosis of tuberculosis when AFB are not detected in spontaneous or induced sputum specimens.