Magnetic resonance imaging in juvenile rheumatoid arthritis.

Magnetic resonance imaging in juvenile rheumatoid arthritis.
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幼年类风湿性关节炎的磁共振成像。

DOI:
10.1016/s0049-0172(97)80015-7
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发表时间:
1997
影响因子:
5
通讯作者:
Passo,MH
Passo,MH
中科院分区:
医学2区
文献类型:
--
作者:
Graham,TB;Blebea,JS;Gylys-Morin,V;Passo,MH

文献摘要

被引文献

相似文献

目的:本研究旨在探讨磁共振成像(MRI)在幼年型类风湿关节炎(JRA)患者治疗中的作用。方法:检索Medline中与MRI相关的文献。进一步检索文献,确定文献中有关JRA和MRI平片成像在成人类风湿关节炎中的应用。儿童和成人的研究表明,MRI在检测滑膜肥大和关节软骨异常方面优于平片。成人的几项研究表明,MR图像与关节镜下的大体解剖学和组织学结果具有良好的相关性。在关节内的结构变化之前发生的生化变化,甚至可以检测到与磁共振spectroscopic.CONCLUSIONSMRI持有承诺的疾病进展inJRA的评估,并可能是有用的系列评价,在临床试验中。
OBJECTIVESThis study was undertaken to examine the role of magneticresonance imaging (MRI) in the management of patients with juvenile rheumatoid arthritis (JRA).METHODSA Medline search was performed to identify all publications pertainingto MRI in JRA. Further searches and identification of articles from bibliographies identified articles pertaining to plain radiograph imaging in JRA and MRI in adult rheumatoid arthritis.RESULTSStudies in both children and adults have shown superiority of MRI toplain radiography in detecting synovial hypertrophy and articular cartilage abnormalities. Several studies in adults have shown a good correlation of MR images with gross anatomic as well as histological findings at arthroscopy. Biochemical changes that occur before structural changes within the joint may even be detectable with magnetic resonance spectroscopy.CONCLUSIONSMRI holds promise for the assessment of disease progression inJRA and may be useful in serial evaluation, as in clinical trials.