Reflectance confocal microscopy of oral epithelial tissue using an electrically tunable lens.
Reflectance confocal microscopy of oral epithelial tissue using an electrically tunable lens.
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使用电可调透镜对口腔上皮组织进行反射共焦显微镜检查。
DOI：
10.1117/12.2037046
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Maitland,KristenC
中科院分区：
文献类型：
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作者：
Jabbour,JoeyM;Malik,BilalH;Cuenca,Rodrigo;Cheng,Shuna;Jo,JavierA;Cheng,Yi-ShingL;Wright,JohnM;Maitland,KristenC
我们提出了一个市售的电可调透镜的使用，以实现轴向扫描的反射共焦显微镜。在255 μm的轴向扫描范围内，横向和轴向分辨率分别为1-2 μm和4-14 μm，取决于可调透镜的可变焦距。对来自口腔离体的正常人活检进行共聚焦成像。使用焦点可调透镜轴向扫描时，在整个上皮深度观察到亚细胞形态学特征。
We present the use of a commercially available electrically tunable lens to achieve axial scanning in a reflectance confocal microscope. Over a 255 μm axial scan range, the lateral and axial resolutions varied from 1-2 μm and 4-14 μm, respectively, dependent on the variable focal length of the tunable lens. Confocal imaging was performed on normal human biopsies from the oral cavity ex vivo. Sub-cellular morphologic features were seen throughout the depth of the epithelium while axially scanning using the focus tunable lens.