Temporal non-linearities of the cochlear amplifier revealed by maximum length sequence stimulation

Temporal non-linearities of the cochlear amplifier revealed by maximum length sequence stimulation
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DOI:
10.1016/s1388-2457(01)00484-9
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发表时间:
2001-05-01
影响因子:
4.7
通讯作者:
Hine, J
Hine, J
中科院分区:
医学3区
文献类型:
--
作者:
Thornton, ARD;Shin, K;Hine, J

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目的:本研究的目的是检查是否耳蜗放大器的时间非线性,所反映的耳声发射(OAEs),存在和不同的任何记录系统nonlinearity.Methods:最大长度序列刺激,在各种刺激率,被用来唤起耳声发射正常听力科目。还从2cc腔中进行了记录。对数据进行分析,以获得第二和第三阶沃尔泰拉核切片的线性响应和估计。这提供了一个衡量两个和3个点击非线性时间相互作用,分别。结果:结果表明,时间的非线性耳声发射确实存在,是稳定的,可重复的个人内,并具有不同于传统的线性响应所示的属性。虽然一些非线性响应特性符合预期的模式,增加幅度与刺激率的增加,有一些领域,他们表现出不可预测的复杂性。结论:虽然可以发现系统的非线性,有没有困难区分生理和系统的非线性组件。新的研究和应用领域可能会导致从使用这些新的OAE响应。(C)2001爱思唯尔科学爱尔兰有限公司版权所有。
Objectives: The objective of this study was to examine whether temporal non-linearities of the cochlear amplifier, as reflected by otoacoustic emissions (OAEs), exist and are distinct from any recordings system non-linearities.Methods: Maximum length sequence stimulation, at various stimulus rates, was used to evoke OAEs from normally hearing subjects. Recordings from a 2cc cavity were also made. The data were analyzed to obtain the linear response and estimates of the slices of the 2nd and 3rd order Volterra kernels. This provided a measure of two and 3 click non-linear temporal interactions, respectively.Results: The results showed that temporal non-linearities of OAEs do exist, are stable and repeatable within individuals and have properties that differ from those shown by the conventional linear response. Whilst some of the non-linear response properties conformed to the expected pattern, of increasing amplitude with increase in stimulus rate, there are some areas in which they show an unpredicted complexity.Conclusions: Whilst system non-linearities could be found, there was no difficulty in distinguishing between the physiological and system non-linear components. New areas of research and application may result from the use of these new OAE responses. (C) 2001 Elsevier Science ireland Ltd. All rights reserved.