Utilisation of water soluble iridium catalysts for signal amplification by reversible exchange
Utilisation of water soluble iridium catalysts for signal amplification by reversible exchange
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DOI：
10.1039/c5dt00311c
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发表时间：
2015-01-01
影响因子：
4
通讯作者：
Duckett, S. B.
中科院分区：
文献类型：
--
作者：
Fekete, M.;Gibard, C.;Duckett, S. B.
通过一系列水溶性铱膦和N-杂环卡宾二氢化物配合物实现了吡啶、3-羟基吡啶和恶唑的可逆交换信号放大（SABRE）过程的催化超极化。虽然SABRE方法在甲醇-d（4）溶液或乙醇-d（6）溶液中的效率高，其中通过[Ir（H）（2）（NCMe）（py）（IMes）（单磺化-三苯基膦）] BF 4产生超过400倍的吡啶H-1极化，但改变为D2 O或D2 O-乙醇溶剂混合物导致活性急剧降低，这在低H-2溶解度方面是合理的。
The catalytic hyperpolarisation of pyridine, 3-hydroxypyridine and oxazole by the Signal Amplification By Reversible Exchange (SABRE) process is achieved by a series of water soluble iridium phosphine and N-heterocyclic carbene dihydride complexes. While the efficiency of the SABRE process in methanol-d(4) solution or ethanol-d(6) solution is high, with over 400-fold H-1 polarisation of pyridine being produced by [Ir(H)(2)(NCMe)(py)(IMes)(monosulfonated-triphenylphosphine)] BF4, changing to a D2O or a D2O-ethanol solvent mixture leads to dramatically reduced activity which is rationalised in terms of low H-2 solubility.