RESISTANCE TO INSULIN IN MENTALLY DISTURBED SOLDIERS
RESISTANCE TO INSULIN IN MENTALLY DISTURBED SOLDIERS
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DOI：
10.1001/archneurpsyc.1946.02300180084007
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发表时间：
1946-01-01
影响因子：
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通讯作者：
FREEMAN, H
中科院分区：
文献类型：
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作者：
FREEMAN, H
对20名正常士兵和93名精神失常士兵进行的一项关于血糖对注射胰岛素反应的敏感性的研究表明，低血糖的平均最高水平（30分钟内）为29.6 mg/ 100 cc。前者为41.4mg./ 100 cc。在后者。这种反应性差异具有统计学显著性。46%的患者显示出比任何正常受试者更不明显的血糖下降。低血糖后继发性血糖升高在两组中相同。所有临床类型的精神障碍患者都注意到这种对胰岛素的依赖性，这可能表明控制血糖调节的内分泌因子的反应性发生了巧合性变化。
A study of the sensitivity of the blood sugar response to injected insulin in a series of 20 normal [male] [male] and of 93 mentally disturbed soldiers revealed that the mean maximum level of hypoglycemia (in 30 mins.) was 29.6 mg./hundred cc. in the former and 41.4 mg./hundred cc. in the latter. This difference in reactivity was statistically significant. Forty-six % of the patients showed a less pronounced drop in blood sugar than any of the normal subjects. The secondary rise in blood sugar following the hypoglycemia was the same in the 2 groups. This resistiveness to insulin was noted with all clinical types of mental disturbance and is probably indicative of a coincidental change in the reactivity of the endocrine factors controlling the regulation of blood sugar.