The effects of regular physical activity on adult-onset asthma incidence in women
The effects of regular physical activity on adult-onset asthma incidence in women
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DOI：
10.1016/j.rmed.2011.03.016
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发表时间：
2011-07-01
影响因子：
4.3
通讯作者：
Garcia-Aymerich, Judith
中科院分区：
文献类型：
--
作者：
Benet, Marta;Varraso, Raphaelle;Garcia-Aymerich, Judith
背景：体育活动对哮喘发病率的潜在益处是稀缺和有争议的。我们的目的是评估定期体育活动与成人发病哮喘之间的关系。方法：我们纳入了来自法国队列研究的51,080名妇女，并从1993年到2003年进行了随访。基线体力活动被定义为花费在家庭和休闲时间体力活动的时间，转换为代谢当量（METs），并按单位分类。随访期间的成人发作哮喘是根据美国胸科学会标准定义的。结果：基线时的平均年龄为53岁，13%的女性目前吸烟，19%的女性超重或肥胖，56%的女性绝经后；512例（1%）患哮喘。在原始或校正后的Cox回归模型中均未发现体力活动与哮喘发病率之间的关联（校正后的HR分别为1.03和1.01，而校正后的HR为1.03和1.01，p为趋势= 0.979）。结论：在这组法国中年妇女中，体力活动与成人发病哮喘无关。(C) 2011 Elsevier Ltd.版权所有。
Background: Potential benefit of physical activity in asthma incidence is scarce and controversial. We aimed to assess the association between regular physical activity and adult-onset asthma.Methods: We included 51,080 women from a French cohort study, and followed them from 1993 to 2003. Physical activity at baseline was defined as time spent in household and leisure time physical activity, converted to metabolic equivalents (METs), and categorised in tertiles. Adult-onset asthma during follow-up was defined according to the American Thoracic Society criteria.Results: Mean age at baseline was 53 years, 13% of women were current smokers, 19% were overweight or obese, and 56% were postmenopausal; 512 (1%) developed asthma. No association was found between physical activity and asthma incidence in the crude or in the adjusted Cox regression model (adjusted HR 1.03 and 1.01 for the 2nd and 3rd tertiles compared to the 1st tertile, p for trend = 0.979).Conclusion: Physical activity is not related to adult-onset asthma in this cohort of French middle-aged women. (C) 2011 Elsevier Ltd. All rights reserved.