CORTICOSTEROIDS IN THE TREATMENT OF SEVERE NOCARDIA PNEUMONIA IN CHRONIC GRANULOMATOUS DISEASE
CORTICOSTEROIDS IN THE TREATMENT OF SEVERE NOCARDIA PNEUMONIA IN CHRONIC GRANULOMATOUS DISEASE
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DOI：
10.1097/inf.0b013e318218181d
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发表时间：
2011-09-01
影响因子：
3.6
通讯作者：
Holland, Steven M.
中科院分区：
文献类型：
--
作者：
Freeman, Alexandra F.;Marciano, Beatriz E.;Holland, Steven M.
诺卡氏菌是慢性肉芽肿病患者感染的5种主要病原菌之一。尽管积极的抗菌治疗，药物治疗并不总是成功的，手术切除感染组织已间歇性需要。我们提出了2例慢性肉芽肿性疾病患者严重诺卡氏菌肺炎的肺部状况恶化，尽管适当的抗菌药物，但随后改善临床和影像学与皮质类固醇。
Nocardia is 1 of the 5 main pathogens that infect chronic granulomatous disease patients. Despite aggressive antimicrobial therapy, medical treatment is not always successful and surgical resection of infected tissue has been intermittently required. We present 2 chronic granulomatous disease patients with severe Nocardia pneumonia whose pulmonary status worsened despite appropriate antimicrobials, but then improved clinically and radiographically with the addition of corticosteroids.