Acute Coronary Syndromes
Acute Coronary Syndromes
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急性冠状动脉综合征
DOI：
10.1201/9780429025396
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
M. Ishihara
中科院分区：
文献类型：
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作者：
S. Honda;Y. Asaumi;M. Fujino;T. Yamane;R. Kumasaka;T. Nagai;Taichi Adachi;Tadayoshi Miyagi;T. Arakawa;M. Nakanishi;H. Sakamoto;J. Kotani;T. Noguchi;Y. Goto;T. Anzai;W. Shimizu;M. Ishihara
背景资料：尽管急性心肌梗死（AMI）的治疗取得了进展，但心源性休克（CS）仍然是导致极高死亡率的最严重的临床并发症。方法：我们评估了2005年至2007年期间入选CREDO-京都AMI登记处的AMI合并CS患者的短期和长期临床结局。实验结果：CREDO-Kyoto AMI登记研究是一项大规模多中心队列研究，在2005年至2007年期间，在日本26家三级医院招募了症状发作后7天内接受冠状动脉血运重建的连续AMI患者。在该登记研究中，连续5206例接受直接经皮冠状动脉介入治疗（PCI）的AMI患者中，712例发生CS。与无CS的患者相比，CS患者的全因死亡风险显著更高（30天时25.1% vs 2.4%，3年时42.0% vs 9.8%，p<0.001）。在CS患者中，与非前壁梗死相比，前壁梗死与更高的全因死亡率显著相关（3年时55.6%对31.7%，p<0.001）。经潜在混杂因素校正后，全因死亡率的独立预测因素为前壁梗死（HR：2.2（1.7-2.8））、年龄大于75岁（HR：1.6（1.2-2.1））、
Background: Despite advances in the treatment of acute myocardial infarction (AMI), cardiogenic shock (CS) is still the most serious clinical complication leading to extremely high mortality. methods: We evaluated short- and long-term clinical outcomes in patients with AMI complicating CS who were enrolled in the CREDO-Kyoto AMI Registry between 2005 and 2007. results: The CREDO-Kyoto AMI registry was a large scale multi-center cohort that enrolled consecutive AMI patients undergoing coronary revascularization within 7 days of the symptom onset between 2005 and 2007 across 26 tertiary hospitals in Japan. Among consecutive 5206 AMI patients having primary percutaneous coronary intervention (PCI) in this registry, 712 patients developed CS. Compared to the patients without CS, the patients with CS had a significantly higher risk for all-cause mortality (25.1% versus 2.4% at 30 days, and 42.0% versus 9.8% at 3 years, p<0.001). In patients with CS, anterior infarction was significantly associated with higher all-cause mortality compared with non-anterior infarction (55.6% versus 31.7% at 3 years, p<0.001). After adjusting by potential confounding factors, independent predictors for all-cause mortality were anterior infarction (HR:2.2 (1.7-2.8)), more than 75 years of age (HR:1.6 (1.2-2.1)), presence of
洗脱支架后十二或30个月的双重抗血小板治疗。
DOI：
10.1056/nejmoa1409312
发表时间：
2014-12-04
期刊：
The New England journal of medicine
影响因子：
--
作者：
Mauri L;Kereiakes DJ;Yeh RW;Driscoll-Shempp P;Cutlip DE;Steg PG;Normand SL;Braunwald E;Wiviott SD;Cohen DJ;Holmes DR Jr;Krucoff MW;Hermiller J;Dauerman HL;Simon DI;Kandzari DE;Garratt KN;Lee DP;Pow TK;Ver Lee P;Rinaldi MJ;Massaro JM;DAPT Study Investigators
通讯作者：
DAPT Study Investigators