Enhancing quality of life and mastery of informal caregivers of high-grade glioma patients: a randomized controlled trial
Enhancing quality of life and mastery of informal caregivers of high-grade glioma patients: a randomized controlled trial
复制标题
DOI：
10.1007/s11060-012-1012-3
复制
发表时间：
2013-02-01
影响因子：
3.9
通讯作者：
Klein, Martin
中科院分区：
文献类型：
--
作者：
Boele, Florien W.;Hoeben, Wopke;Klein, Martin
高级别胶质瘤（HGG）是严重的原发性脑肿瘤，可能会阻止患者在社会，情感和认知方面的正常功能。伴侣的角色通常会转变为非正式的照顾者。因此，他们可能会遇到显着的压力和减少照顾者掌握，负面影响他们的健康相关的生活质量（HRQOL）。我们的目的是（1）确定影响HGG患者HRQOL和照顾者掌握的因素，（2）调查由心理教育和认知行为治疗组成的结构化干预是否会改善HRQOL的心理部分和照顾者的掌握。五十六人被随机分配到干预组或常规护理组。干预计划包括与心理学家进行的六次一小时的会议。参与者在基线（即随机化前）和此后每2个月直至8个月后完成了关于他们对患者HRQOL（SF-36）、神经功能（BN 20）和认知功能（MOS）的看法以及关于他们自己的HRQOL（SF-36）和护理人员掌握感（CMS）的问卷调查，共5次。患者的HRQOL和神经功能被发现与HRQOL和非正式照顾者在基线时的掌控感有关。干预帮助照顾者在保持一个稳定的HRQOL水平，并改善了8个月的时间内掌握的感觉。我们的研究结果表明，非正式的照顾者可以受益于心理干预，因为它是一个有用的工具，在保持稳定的心理功能和照顾者掌握水平。
High-grade gliomas (HGG) are serious primary brain tumors that may prevent the patient from functioning normally in social, emotional and cognitive respect. Often the partner's role will convert to that of informal caregiver. Consequently, they may experience significant stress and reductions in caregiver mastery, negatively affecting their health-related quality of life (HRQOL). We aimed at (1) determining factors that impact HRQOL and mastery of caregivers of HGG patients, and (2) investigate if a structured intervention consisting of psychoeducation and cognitive behavioral therapy leads to improvements in the mental component of HRQOL and mastery of caregivers. Fifty-six patient-caregiver dyads were randomly assigned to the intervention group or the care as usual group. The intervention program consisted of six one-hour sessions with a psychologist. Participants completed questionnaires concerning their perceptions of the patients' HRQOL (SF-36), neurological functioning (BN20), and cognitive functioning (MOS), and concerning their own HRQOL (SF-36) and feelings of caregiver mastery (CMS) both at baseline (i.e. before randomization) and every 2 months thereafter until 8 months later, five times in total. Patients' HRQOL and neurological functioning were found to be related to HRQOL and feelings of mastery of the informal caregiver at baseline. The intervention helped caregivers in maintaining a stable level of HRQOL and improved feelings of mastery over an 8 month period. Our findings suggest that informal caregivers can benefit from a psychological intervention as it is a helpful tool in maintaining a stable level of mental functioning and caregiver mastery.