Do migrating cells need a nucleus?

Do migrating cells need a nucleus?
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DOI:
10.1083/jcb.201802054
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发表时间:
2018-03-05
期刊:
The Journal of cell biology
影响因子:
--
通讯作者:
Hawkins RJ
Hawkins RJ
中科院分区:
其他
文献类型:
--
作者:
Hawkins RJ

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Hawkins previews work from Graham et al. describing the role of the nucleus in cell polarity and migration. How the nucleus affects cell polarity and migration is unclear. In this issue, Graham et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201706097) show that enucleated cells polarize and migrate in two but not three dimensions and propose that the nucleus is a necessary component of the molecular clutch regulating normal mechanical responses.
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