Closed-loop adaptive optics in the human eye

Closed-loop adaptive optics in the human eye
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DOI:
10.1364/ol.26.000746
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发表时间:
2001-05-15
期刊:
影响因子:
3.6
通讯作者:
Artal, P
Artal, P
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
Fernández, EJ;Iglesias, I;Artal, P

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我们开发了一种用于人眼像差实时闭环测量和校正的原型装置。该仪器使用红外光源,利用哈特曼-夏克传感器测量25 Hz的波前像差。离焦由电动验光仪去除,高阶像差由膜变形镜校正。该设备首先在一只人造眼睛上进行了测试。静态像差的校正大约需要五次迭代,使系统能够跟随5 Hz的像差变化。这种能力允许人们跟踪眼睛中的大部分像差动态。结果显示,活体眼睛对像差进行了有效的闭环校正,在4.3 mm瞳孔直径下,残余未校正波前为0.1 mm。采用自适应像差校正和不采用自适应像差校正的方法对不同受试者的点光源视网膜图像进行实时估计。结果表明,该方法可以实时闭环校正活体眼像差。这种装置的一个应用是作为电光“眼镜”来改善视力。(C) 2001美国光学学会。
We have developed a prototype apparatus for real-time closed-loop measurement and correction of aberrations in the human eye. The apparatus uses infrared light to measure the wave-front aberration at 25 Hz with a Hartmann-Shack sensor. Defocus is removed by a motorized optometer, and higher-order aberrations are corrected by a membrane deformable mirror. The device was first tested with an artificial eye. Correction of static aberrations takes approximately five iterations, making the system capable of following aberration changes at 5 Hz. This capability allows one to track most of the aberration dynamics in the eye. Results in living eyes showed effective closed-loop correction of aberrations, with a residual uncorrected wave front of 0.1 mum for a 4.3-mm pupil diameter. Retinal images of a point source in different subjects with and without adaptive correction of aberrations were estimated in real time. The results demonstrate real-time closed-loop correction of aberration in the living eye. An application of this device is as electro-optic "spectacles" to improve vision. (C) 2001 Optical Society of America.