[A case of acute type adult T cell leukemia and human T-lymphotropic virus type I associated myelopathy who presented meningitis and polyradiculoneuropathy and improved with steroid treatment].
[A case of acute type adult T cell leukemia and human T-lymphotropic virus type I associated myelopathy who presented meningitis and polyradiculoneuropathy and improved with steroid treatment].
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[一例急性成人T细胞白血病和人类T淋巴细胞病毒I型相关性脊髓病，表现为脑膜炎和多发性神经根神经病，经类固醇治疗后好转]。
DOI：
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发表时间：
2000
期刊：
影响因子：
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通讯作者：
K. Sugita
中科院分区：
文献类型：
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作者：
N. Kasahata;M. Kawamura;J. Shiota;Y. Miyazawa;Y. Suzuki;K. Sugita
我们报告一位35岁男性急性型成人T细胞白血病（ATL）合并人类T淋巴细胞病毒I型相关性脊髓病。他出现脑膜炎和多发性神经根神经病，经类固醇治疗后好转。他出现头痛和感觉性共济失调，这些症状对类固醇治疗有反应。ATL的常见临床特征在发病时不存在。脑脊液中存在ATL样细胞，血液中存在HTLV-Ⅰ前病毒DNA。因此，我们推测感染细胞存在单克隆增生。他在缓解2年后出现了ATL。提示脑膜炎和多发性神经根神经病患者存在急性型ATL，激素治疗有效。
We reported a 35-year-old male patient with acute type adult T cell leukemia(ATL) and human T-lymphotropic virus type I associated myelopathy. He presented meningitis and polyradiculoneuropathy and improved with steroid treatment. He presented headache and sensory ataxia and these symptoms responded to steroid treatment. The usual clinical features of ATL were absent at onset. There existed ATL-like cells in the cerebrospinal fluid and HTLV-I proviral DNA in the blood. Therefore, we surmised that there was monoclonal hyperplasia of the infected cells. He presented ATL after 2 years remission. We pointed out that there was acute type of ATL in patients with meningitis and polyradiculoneuropathy, for which steroid treatment could be effective.