Intracerebral haemorrhage and COVID-19: Clinical characteristics from a case series

Intracerebral haemorrhage and COVID-19: Clinical characteristics from a case series
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DOI:
10.1016/j.bbi.2020.06.005
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发表时间:
2020-08-01
影响因子:
15.1
通讯作者:
Sztriha, Laszlo
Sztriha, Laszlo
中科院分区:
医学1区
文献类型:
--
作者:
Benger, Matthew;Williams, Owain;Sztriha, Laszlo

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2.方法在这个回顾性病例系列中,我们使用放射信息系统进行了全医院范围的搜索,查看了2020年2月1日至2020年5月14日在KCH进行的所有CT头部检查的报告。所有的扫描都是由神经放射科顾问医生报告或审查的。对于所有显示脑出血的扫描,我们使用电子患者记录来识别患者的新冠肺炎状态。用逆转录聚合酶链式反应(RT-PCR)对鼻咽拭子进行SARS-CoV-2核酸检测。如果患者在脑出血前新冠肺炎检测呈阳性,并有与新冠肺炎相关的持续临床特征,则被纳入病例系列。所有患者均获得知情同意。结果我们确定了5名患者,他们都有脑出血的放射学证据,并经RT-PCR证实为新冠肺炎。我们描述了它们的临床特征、影像表现、实验室数据和临床病程(表1)。
2. MethodsIn this retrospective case series, we performed a hospital-wide search using the Radiology Information System looking at the reports of all Computed Tomography (CT) head examinations that had been performed from 1st February 2020 to 14th May 2020 at KCH. All scans were reported or reviewed by a consultant neuroradiologist. For all scans that had demonstrated ICH we identified the COVID-19 status of the patient using electronic patient records. SARS-CoV-2 nucleic acid tests were performed on nasopharyngeal swabs using reverse transcriptase-polymerase chain reaction (RT-PCR). Patients were included in the case series if they had tested positive for COVID-19 prior to their ICH and had continuing clinical features related to COVID-19. Informed consent was obtained for all patients.3. ResultsWe identified five patients who presented with radiographic evidence of ICH and RT-PCR-confirmed COVID-19. We describe their clinical characteristics, imaging findings, laboratory data, and clinical course (Table 1).