Upper socioeconomic status is associated with lower Helicobacter pylori infection rate among patients undergoing gastroscopy
Upper socioeconomic status is associated with lower Helicobacter pylori infection rate among patients undergoing gastroscopy
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DOI：
10.3855/jidc.11877
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发表时间：
2020-03-01
影响因子：
1.9
通讯作者：
Mungan, Zeynel
中科院分区：
文献类型：
--
作者：
Attila, Tan;Zeybel, Mujdat;Mungan, Zeynel
简介：社会经济因素在幽门螺杆菌（HP）感染的患病率中发挥着重要作用。本研究的目的是调查在流行病城市地区接受胃镜检查的社会经济上层人群中有症状的患者中 HP 患病率。方法：在 12 个月的时间内，从第一批连续 1000 名接受胃镜检查和 HP 评估的患者（大学医院 500 名，社区医院 500 名）收集数据。结果：总体而言，211/1000 名患者 (21.1 %) 发现胃部有 HP活检。快速尿素酶试验的特异性、敏感性、阳性预测值、阴性预测值和诊断准确率分别为87.5%、99.7%、99%、96.5%和96.9%。 HP 阳性患者中萎缩性胃炎、胃和十二指肠溃疡明显更常见。 HP 患病率的年龄分布：> 6 岁（15.5%）、3-5 岁（26.1%）、< 3 岁（10.4%）。结论：在 HP 流行国家，属于社会经济上层人群的有症状患者的 HP 感染患病率似乎明显较低。年轻患者的患病率最低，预计未来 HP 患病率会下降。
Introduction: Socioeconomic factors play an important role in the prevalence of Helicobacter pylori (HP) infection. The aim of this study is to investigate HP prevalence among symptomatic patients in the upper socioeconomic segment of the population undergoing gastroscopy in an endemic urban region.Methodology: Over a 12-month period, data were collected from the first consecutive 1000 patients (500 from university hospital, 500 from community hospital) who had gastroscopy and HP evaluation.Results: Overall, 211/1000 patients (21.1 %) were found to have HP in gastric biopsies. The specificity, sensitivity, positive predictive value, negative predictive value and diagnostic accuracy of rapid urease test were 87.5%, 99.7%, 99%, 96.5%, and 96.9% respectively. Atrophic gastritis, gastric and duodenal ulcers were significantly more common in HP positive patients. Age based distribution of HP prevalence: > 6 decades (15.5%), 3rd-5th decades (26.1%), < 3rd decades (10.4%).Conclusion: In an HP endemic country, the prevalence of HP infection among symptomatic patients belonging to the upper socioeconomic segment of the population appears to be markedly lower. The lowest prevalence in young patients is expected to result in future decrease in HP prevalence.