Argentine ant extract induces an osm-9 dependent chemotaxis response in C. elegans.
Argentine ant extract induces an osm-9 dependent chemotaxis response in C. elegans.
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阿根廷蚂蚁提取物诱导秀丽隐杆线虫的 osm-9 依赖性趋化反应。
DOI：
10.17912/micropub.biology.000745
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发表时间：
2023
影响因子：
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通讯作者：
O'Connell, Lauren A
中科院分区：
文献类型：
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作者：
Alfonso, Sebastian A;Arango Sumano, Daniel;Bhatt, Dhruv A;Cullen, Aidan B;Hajian, Cyrus M;Huang, Winnie;Jaeger, Emma L;Li, Emily;Maske, A Kaile;Offenberg, Emma G;Ta, Vy;Whiting, Waymon W;Adebogun, Grace T;Bachmann, Annabelle E;Callan, Ashlyn A;Khan, Ummara;Lewis, Amaris R;Pollock, Alexa C;Ramirez, Dave;Bradon, Nicole;Fiocca, Katherine;Cote, Lauren E;Sallee, Maria D;McKinney, Jordan;O'Connell, Lauren A
许多蚂蚁物种都具有化学防御能力，尽管这些化合物如何影响神经系统功能尚不清楚。在这里，我们研究了秀丽隐杆线虫趋化性测定的效用，以调查蚂蚁化学防御化合物是如何被异源神经系统检测到的。我们发现C.秀丽线虫对入侵的阿根廷蚂蚁（Linepithemahumile）的提取物有反应，而这种反应需要osm-9离子通道。不同菌株对L.谦卑的提取物，表明趋化反应的遗传变异。这些实验是由一个本科实验室课程进行的，强调了C。在教室环境中进行的线虫趋化性测定可以提供真正的研究经验，并揭示物种间相互作用的新见解。
Many ant species are equipped with chemical defenses, although how these compounds impact nervous system function is unclear. Here, we examined the utility of Caenorhabditis elegans chemotaxis assays for investigating how ant chemical defense compounds are detected by heterospecific nervous systems. We found that C. elegans respond to extracts from the invasive Argentine Ant ( Linepithema humile ) and the osm-9 ion channel is required for this response. Divergent strains varied in their response to L. humile extracts, suggesting genetic variation underlying chemotactic responses. These experiments were conducted by an undergraduate laboratory course, highlighting how C. elegans chemotaxis assays in a classroom setting can provide genuine research experiences and reveal new insights into interspecies interactions.